HCSGD entry for GLRX3
1. General information
| Official gene symbol | GLRX3 |
|---|---|
| Entrez ID | 10539 |
| Gene full name | glutaredoxin 3 |
| Other gene symbols | GLRX4 GRX3 GRX4 PICOT TXNL2 TXNL3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002026 | Regulation of the force of heart contraction | ISS | biological_process |
| GO:0005080 | Protein kinase C binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005938 | Cell cortex | IEA | cellular_component |
| GO:0009055 | Electron carrier activity | IEA | molecular_function |
| GO:0010614 | Negative regulation of cardiac muscle hypertrophy | ISS | biological_process |
| GO:0015035 | Protein disulfide oxidoreductase activity | IEA | molecular_function |
| GO:0030018 | Z disc | IEA | cellular_component |
| GO:0045454 | Cell redox homeostasis | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051536 | Iron-sulfur cluster binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0965447513 | 0.7848553474 | 0.6491022222 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3332419127 |
| GSE13712_SHEAR | Up | 0.0724941587 |
| GSE13712_STATIC | Up | 0.1671506535 |
| GSE19018 | Down | -0.2063227893 |
| GSE19899_A1 | Up | 0.3941134436 |
| GSE19899_A2 | Up | 0.4237137240 |
| PubMed_21979375_A1 | Up | 0.3925447922 |
| PubMed_21979375_A2 | Up | 0.2626432978 |
| GSE35957 | Down | -0.2459744613 |
| GSE36640 | Down | -0.0479600805 |
| GSE54402 | Up | 0.5231114952 |
| GSE9593 | Up | 0.0805984066 |
| GSE43922 | Up | 0.5244402811 |
| GSE24585 | Down | -0.5025725009 |
| GSE37065 | Down | -0.0798523160 |
| GSE28863_A1 | Up | 0.1974237991 |
| GSE28863_A2 | Up | 0.1697240941 |
| GSE28863_A3 | Down | -0.1812453576 |
| GSE28863_A4 | Up | 0.0090975789 |
| GSE48662 | Down | -0.5384823333 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028654 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
