HCSGD entry for SEMA3C


1. General information

Official gene symbolSEMA3C
Entrez ID10512
Gene full namesema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Other gene symbolsSEMAE SemE
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001755Neural crest cell migrationIEAbiological_process
GO:0001756SomitogenesisIEAbiological_process
GO:0001974Blood vessel remodelingIEAbiological_process
GO:0003151Outflow tract morphogenesisIEAbiological_process
GO:0003215Cardiac right ventricle morphogenesisIEAbiological_process
GO:0003350Pulmonary myocardium developmentIEAbiological_process
GO:0004872Receptor activityIEAmolecular_function
GO:0005615Extracellular spaceIEAcellular_component
GO:0006955Immune responseTASbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007411Axon guidanceISSbiological_process
GO:0009791Post-embryonic developmentIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0021915Neural tube developmentIEAbiological_process
GO:0030215Semaphorin receptor bindingIEAmolecular_function
GO:0042493Response to drugTASbiological_process
GO:0060174Limb bud formationIEAbiological_process
GO:0060666Dichotomous subdivision of terminal units involved in salivary gland branchingIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00027305570.96965820070.04536415091.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.4543394062
GSE13712_SHEARDown-0.0150434726
GSE13712_STATICUp0.0887276848
GSE19018Up0.0217229572
GSE19899_A1Up1.6855648563
GSE19899_A2Up0.7577829601
PubMed_21979375_A1Up2.2306076600
PubMed_21979375_A2Up1.5446779196
GSE35957Up0.3188624408
GSE36640Up0.5497217202
GSE54402Up0.1726297214
GSE9593Up0.1897936112
GSE43922Up1.4634090347
GSE24585Up1.0649007296
GSE37065Up0.0942649459
GSE28863_A1Up1.1724199912
GSE28863_A2Up1.5631210711
GSE28863_A3Up0.5287567665
GSE28863_A4Up0.2336905621
GSE48662Down-0.3281314567

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-374b-5pMIMAT0004955MIRT016050SequencingFunctional MTI (Weak)20371350
hsa-miR-375MIMAT0000728MIRT019941MicroarrayFunctional MTI (Weak)20215506
hsa-miR-98-5pMIMAT0000096MIRT027705MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.