HCSGD entry for SEMA3C
1. General information
| Official gene symbol | SEMA3C |
|---|---|
| Entrez ID | 10512 |
| Gene full name | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| Other gene symbols | SEMAE SemE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001755 | Neural crest cell migration | IEA | biological_process |
| GO:0001756 | Somitogenesis | IEA | biological_process |
| GO:0001974 | Blood vessel remodeling | IEA | biological_process |
| GO:0003151 | Outflow tract morphogenesis | IEA | biological_process |
| GO:0003215 | Cardiac right ventricle morphogenesis | IEA | biological_process |
| GO:0003350 | Pulmonary myocardium development | IEA | biological_process |
| GO:0004872 | Receptor activity | IEA | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0007411 | Axon guidance | ISS | biological_process |
| GO:0009791 | Post-embryonic development | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0021915 | Neural tube development | IEA | biological_process |
| GO:0030215 | Semaphorin receptor binding | IEA | molecular_function |
| GO:0042493 | Response to drug | TAS | biological_process |
| GO:0060174 | Limb bud formation | IEA | biological_process |
| GO:0060666 | Dichotomous subdivision of terminal units involved in salivary gland branching | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0002730557 | 0.9696582007 | 0.0453641509 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4543394062 |
| GSE13712_SHEAR | Down | -0.0150434726 |
| GSE13712_STATIC | Up | 0.0887276848 |
| GSE19018 | Up | 0.0217229572 |
| GSE19899_A1 | Up | 1.6855648563 |
| GSE19899_A2 | Up | 0.7577829601 |
| PubMed_21979375_A1 | Up | 2.2306076600 |
| PubMed_21979375_A2 | Up | 1.5446779196 |
| GSE35957 | Up | 0.3188624408 |
| GSE36640 | Up | 0.5497217202 |
| GSE54402 | Up | 0.1726297214 |
| GSE9593 | Up | 0.1897936112 |
| GSE43922 | Up | 1.4634090347 |
| GSE24585 | Up | 1.0649007296 |
| GSE37065 | Up | 0.0942649459 |
| GSE28863_A1 | Up | 1.1724199912 |
| GSE28863_A2 | Up | 1.5631210711 |
| GSE28863_A3 | Up | 0.5287567665 |
| GSE28863_A4 | Up | 0.2336905621 |
| GSE48662 | Down | -0.3281314567 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016050 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-375 | MIMAT0000728 | MIRT019941 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027705 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
