HCSGD entry for WFDC2
1. General information
| Official gene symbol | WFDC2 |
|---|---|
| Entrez ID | 10406 |
| Gene full name | WAP four-disulfide core domain 2 |
| Other gene symbols | EDDM4 HE4 WAP5 dJ461P17.6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004866 | Endopeptidase inhibitor activity | TAS | molecular_function |
| GO:0004867 | Serine-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0004869 | Cysteine-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0006508 | Proteolysis | TAS | biological_process |
| GO:0007283 | Spermatogenesis | TAS | biological_process |
| GO:0010951 | Negative regulation of endopeptidase activity | TAS | biological_process |
| GO:0019828 | Aspartic-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0030414 | Peptidase inhibitor activity | IEA | molecular_function |
| GO:0052548 | Regulation of endopeptidase activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6454001596 | 0.8527979256 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0881338432 |
| GSE13712_SHEAR | Up | 0.0472650708 |
| GSE13712_STATIC | Up | 0.0362265388 |
| GSE19018 | Up | 0.0471780815 |
| GSE19899_A1 | Up | 0.0805474719 |
| GSE19899_A2 | Up | 0.0467991979 |
| PubMed_21979375_A1 | Up | 0.0173967360 |
| PubMed_21979375_A2 | Down | -0.0915470731 |
| GSE35957 | Up | 0.0788761692 |
| GSE36640 | Up | 0.0519098825 |
| GSE54402 | Down | -0.0552543621 |
| GSE9593 | Up | 0.0580319375 |
| GSE43922 | Up | 0.1829589375 |
| GSE24585 | Up | 0.0143989531 |
| GSE37065 | Up | 0.0054212861 |
| GSE28863_A1 | Down | -0.0773176786 |
| GSE28863_A2 | Up | 0.1000973004 |
| GSE28863_A3 | Up | 0.3642595136 |
| GSE28863_A4 | Down | -0.0838156638 |
| GSE48662 | Down | -0.0764333568 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
