HCSGD entry for WFDC2

1. General information

Official gene symbolWFDC2
Entrez ID10406
Gene full nameWAP four-disulfide core domain 2
Other gene symbolsEDDM4 HE4 WAP5 dJ461P17.6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004866Endopeptidase inhibitor activityTASmolecular_function
GO:0004867Serine-type endopeptidase inhibitor activityIEAmolecular_function
GO:0004869Cysteine-type endopeptidase inhibitor activityIEAmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005615Extracellular spaceTAScellular_component
GO:0006508ProteolysisTASbiological_process
GO:0007283SpermatogenesisTASbiological_process
GO:0010951Negative regulation of endopeptidase activityTASbiological_process
GO:0019828Aspartic-type endopeptidase inhibitor activityIEAmolecular_function
GO:0030414Peptidase inhibitor activityIEAmolecular_function
GO:0052548Regulation of endopeptidase activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.64540015960.85279792560.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0881338432
GSE13712_SHEARUp0.0472650708
GSE13712_STATICUp0.0362265388
GSE19018Up0.0471780815
GSE19899_A1Up0.0805474719
GSE19899_A2Up0.0467991979
PubMed_21979375_A1Up0.0173967360
PubMed_21979375_A2Down-0.0915470731
GSE35957Up0.0788761692
GSE36640Up0.0519098825
GSE54402Down-0.0552543621
GSE9593Up0.0580319375
GSE43922Up0.1829589375
GSE24585Up0.0143989531
GSE37065Up0.0054212861
GSE28863_A1Down-0.0773176786
GSE28863_A2Up0.1000973004
GSE28863_A3Up0.3642595136
GSE28863_A4Down-0.0838156638
GSE48662Down-0.0764333568

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.