HCSGD entry for SEMA3A

1. General information

Official gene symbolSEMA3A
Entrez ID10371
Gene full namesema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
Other gene symbolsCOLL1 Hsema-I Hsema-III SEMA1 SEMAD SEMAIII SEMAL SemD coll-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001764Neuron migrationIEA ISSbiological_process
GO:0002027Regulation of heart rateIEAbiological_process
GO:0004872Receptor activityIEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0007413Axonal fasciculationIEAbiological_process
GO:0010633Negative regulation of epithelial cell migrationIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0021675Nerve developmentISSbiological_process
GO:0021772Olfactory bulb developmentIMPbiological_process
GO:0030215Semaphorin receptor bindingIEAmolecular_function
GO:0030424AxonIEAcellular_component
GO:0030425DendriteIEAcellular_component
GO:0045499Chemorepellent activityIEA TASmolecular_function
GO:0048485Sympathetic nervous system developmentTASbiological_process
GO:0048813Dendrite morphogenesisIEAbiological_process
GO:0048841Regulation of axon extension involved in axon guidanceIDAbiological_process
GO:0048843Negative regulation of axon extension involved in axon guidanceIEAbiological_process
GO:0048846Axon extension involved in axon guidanceIEA ISSbiological_process
GO:0048880Sensory system developmentTASbiological_process
GO:0060385Axonogenesis involved in innervationIEA ISSbiological_process
GO:0060666Dichotomous subdivision of terminal units involved in salivary gland branchingIEAbiological_process
GO:0061549Sympathetic ganglion developmentIEA ISSbiological_process
GO:0071526Semaphorin-plexin signaling pathwayTASbiological_process
GO:0097490Sympathetic neuron projection extensionIEA ISSbiological_process
GO:0097491Sympathetic neuron projection guidanceIEA ISSbiological_process
GO:1902285Semaphorin-plexin signaling pathway involved in neuron projection guidanceIEA ISSbiological_process
GO:2001224Positive regulation of neuron migrationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01474586830.07908655830.30251441930.5317081226

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5954885341
GSE13712_SHEARUp2.0829447399
GSE13712_STATICUp2.1521535317
GSE19018Down-0.1662821582
GSE19899_A1Up0.0260243189
GSE19899_A2Down-1.3383711081
PubMed_21979375_A1Down-0.1686977678
PubMed_21979375_A2Down-0.4527393230
GSE35957Up1.2660858852
GSE36640Down-0.0806289374
GSE54402Down-0.5509396938
GSE9593Up0.1671519856
GSE43922Up0.1052871423
GSE24585Down-0.7869230939
GSE37065Up1.3627932201
GSE28863_A1Up0.0789374666
GSE28863_A2Up0.7886146209
GSE28863_A3Down-1.1281054982
GSE28863_A4Up0.1552173943
GSE48662Down-0.3135240728

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.