HCSGD entry for TRIM22
1. General information
| Official gene symbol | TRIM22 |
|---|---|
| Entrez ID | 10346 |
| Gene full name | tripartite motif containing 22 |
| Other gene symbols | GPSTAF50 RNF94 STAF50 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0003714 | Transcription corepressor activity | TAS | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | TAS | biological_process |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0009615 | Response to virus | TAS | biological_process |
| GO:0015030 | Cajal body | IEA | cellular_component |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0051607 | Defense response to virus | IEA | biological_process |
| GO:0070206 | Protein trimerization | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0362505110 | 0.0245883515 | 0.4325247960 | 0.3021428571 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2215846381 |
| GSE13712_SHEAR | Up | 0.2595049338 |
| GSE13712_STATIC | Up | 0.2130754359 |
| GSE19018 | Up | 1.2390420932 |
| GSE19899_A1 | Down | -1.2249323838 |
| GSE19899_A2 | Up | 0.0256963675 |
| PubMed_21979375_A1 | Down | -3.1514739071 |
| PubMed_21979375_A2 | Down | -0.3300257144 |
| GSE35957 | Down | -0.4616152148 |
| GSE36640 | Up | 2.6026322438 |
| GSE54402 | Down | -1.7917409933 |
| GSE9593 | Up | 0.4492844462 |
| GSE43922 | Down | -0.9619945445 |
| GSE24585 | Up | 0.5159663558 |
| GSE37065 | Up | 0.7294374972 |
| GSE28863_A1 | Down | -0.0135655358 |
| GSE28863_A2 | Down | -0.0989495999 |
| GSE28863_A3 | Down | -0.5091500166 |
| GSE28863_A4 | Up | 0.1530349947 |
| GSE48662 | Up | 0.1332752326 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018054 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-146a-5p | MIMAT0000449 | MIRT021245 | Microarray | Functional MTI (Weak) | 18057241 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029579 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
