HCSGD entry for TRIM22


1. General information

Official gene symbolTRIM22
Entrez ID10346
Gene full nametripartite motif containing 22
Other gene symbolsGPSTAF50 RNF94 STAF50
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedTASbiological_process
GO:0006955Immune responseTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0009615Response to virusTASbiological_process
GO:0015030Cajal bodyIEAcellular_component
GO:0016032Viral processIEAbiological_process
GO:0016567Protein ubiquitinationIEAbiological_process
GO:0016607Nuclear speckIEAcellular_component
GO:0016874Ligase activityIEAmolecular_function
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0051607Defense response to virusIEAbiological_process
GO:0070206Protein trimerizationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03625051100.02458835150.43252479600.3021428571

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2215846381
GSE13712_SHEARUp0.2595049338
GSE13712_STATICUp0.2130754359
GSE19018Up1.2390420932
GSE19899_A1Down-1.2249323838
GSE19899_A2Up0.0256963675
PubMed_21979375_A1Down-3.1514739071
PubMed_21979375_A2Down-0.3300257144
GSE35957Down-0.4616152148
GSE36640Up2.6026322438
GSE54402Down-1.7917409933
GSE9593Up0.4492844462
GSE43922Down-0.9619945445
GSE24585Up0.5159663558
GSE37065Up0.7294374972
GSE28863_A1Down-0.0135655358
GSE28863_A2Down-0.0989495999
GSE28863_A3Down-0.5091500166
GSE28863_A4Up0.1530349947
GSE48662Up0.1332752326

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018054MicroarrayFunctional MTI (Weak)18185580
hsa-miR-146a-5pMIMAT0000449MIRT021245MicroarrayFunctional MTI (Weak)18057241
hsa-miR-26b-5pMIMAT0000083MIRT029579MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.