HCSGD entry for IRX5
1. General information
| Official gene symbol | IRX5 |
|---|---|
| Entrez ID | 10265 |
| Gene full name | iroquois homeobox 5 |
| Other gene symbols | HMMS IRX-2a IRXB2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002027 | Regulation of heart rate | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005499 | Vitamin D binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0008406 | Gonad development | IMP | biological_process |
| GO:0042551 | Neuron maturation | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0048701 | Embryonic cranial skeleton morphogenesis | IMP | biological_process |
| GO:0050896 | Response to stimulus | IEA | biological_process |
| GO:0060040 | Retinal bipolar neuron differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8505280840 | 0.1948002128 | 0.9999902473 | 0.8553733167 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0494177728 |
| GSE13712_SHEAR | Down | -0.1630273262 |
| GSE13712_STATIC | Down | -0.2713808317 |
| GSE19018 | Down | -0.0181234919 |
| GSE19899_A1 | Up | 0.0102403060 |
| GSE19899_A2 | Up | 0.0963506338 |
| PubMed_21979375_A1 | Down | -0.2075614568 |
| PubMed_21979375_A2 | Down | -0.0396755508 |
| GSE35957 | Down | -0.9717264118 |
| GSE36640 | Up | 0.0408712759 |
| GSE54402 | Up | 0.0843013225 |
| GSE9593 | Down | -0.3544896196 |
| GSE43922 | Up | 0.1004513023 |
| GSE24585 | Up | 0.0153265334 |
| GSE37065 | Down | -0.0388129487 |
| GSE28863_A1 | Down | -0.0952450849 |
| GSE28863_A2 | Down | -0.3990496979 |
| GSE28863_A3 | Up | 0.0284690901 |
| GSE28863_A4 | Down | -0.0260283304 |
| GSE48662 | Up | 0.2526480329 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
