HCSGD entry for IRX5


1. General information

Official gene symbolIRX5
Entrez ID10265
Gene full nameiroquois homeobox 5
Other gene symbolsHMMS IRX-2a IRXB2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002027Regulation of heart rateIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005499Vitamin D bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0008406Gonad developmentIMPbiological_process
GO:0042551Neuron maturationIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0048701Embryonic cranial skeleton morphogenesisIMPbiological_process
GO:0050896Response to stimulusIEAbiological_process
GO:0060040Retinal bipolar neuron differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.85052808400.19480021280.99999024730.8553733167

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0494177728
GSE13712_SHEARDown-0.1630273262
GSE13712_STATICDown-0.2713808317
GSE19018Down-0.0181234919
GSE19899_A1Up0.0102403060
GSE19899_A2Up0.0963506338
PubMed_21979375_A1Down-0.2075614568
PubMed_21979375_A2Down-0.0396755508
GSE35957Down-0.9717264118
GSE36640Up0.0408712759
GSE54402Up0.0843013225
GSE9593Down-0.3544896196
GSE43922Up0.1004513023
GSE24585Up0.0153265334
GSE37065Down-0.0388129487
GSE28863_A1Down-0.0952450849
GSE28863_A2Down-0.3990496979
GSE28863_A3Up0.0284690901
GSE28863_A4Down-0.0260283304
GSE48662Up0.2526480329

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.