HCSGD entry for DHRS2


1. General information

Official gene symbolDHRS2
Entrez ID10202
Gene full namedehydrogenase/reductase (SDR family) member 2
Other gene symbolsHEP27 SDR25C1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004090Carbonyl reductase (NADPH) activityIDAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005635Nuclear envelopeIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0005759Mitochondrial matrixIEAcellular_component
GO:0008207C21-steroid hormone metabolic processNASbiological_process
GO:0008285Negative regulation of cell proliferationNASbiological_process
GO:0009636Response to toxic substanceIDAbiological_process
GO:0016491Oxidoreductase activityIEAmolecular_function
GO:0034599Cellular response to oxidative stressIDAbiological_process
GO:0043011Myeloid dendritic cell differentiationIEPbiological_process
GO:0043066Negative regulation of apoptotic processIMPbiological_process
GO:0055114Oxidation-reduction processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.41222689490.49116836370.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3158803423
GSE13712_SHEARUp0.0766691987
GSE13712_STATICDown-0.0155055187
GSE19018Up0.0239359721
GSE19899_A1Down-0.0920584372
GSE19899_A2Up0.0704167420
PubMed_21979375_A1Down-0.3735434636
PubMed_21979375_A2Down-0.3185368534
GSE35957Down-0.5134418936
GSE36640Down-0.5714410912
GSE54402Down-0.0020553610
GSE9593Up0.0893192782
GSE43922Up0.0125365483
GSE24585Up1.0524156855
GSE37065Up0.0846556593
GSE28863_A1Down-0.0765561863
GSE28863_A2Down-0.1544804240
GSE28863_A3Up0.0748881885
GSE28863_A4Up0.0366669262
GSE48662Up0.2260327343

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.