HCSGD entry for DHRS2
1. General information
| Official gene symbol | DHRS2 |
|---|---|
| Entrez ID | 10202 |
| Gene full name | dehydrogenase/reductase (SDR family) member 2 |
| Other gene symbols | HEP27 SDR25C1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004090 | Carbonyl reductase (NADPH) activity | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005635 | Nuclear envelope | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005759 | Mitochondrial matrix | IEA | cellular_component |
| GO:0008207 | C21-steroid hormone metabolic process | NAS | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | NAS | biological_process |
| GO:0009636 | Response to toxic substance | IDA | biological_process |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0034599 | Cellular response to oxidative stress | IDA | biological_process |
| GO:0043011 | Myeloid dendritic cell differentiation | IEP | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IMP | biological_process |
| GO:0055114 | Oxidation-reduction process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4122268949 | 0.4911683637 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3158803423 |
| GSE13712_SHEAR | Up | 0.0766691987 |
| GSE13712_STATIC | Down | -0.0155055187 |
| GSE19018 | Up | 0.0239359721 |
| GSE19899_A1 | Down | -0.0920584372 |
| GSE19899_A2 | Up | 0.0704167420 |
| PubMed_21979375_A1 | Down | -0.3735434636 |
| PubMed_21979375_A2 | Down | -0.3185368534 |
| GSE35957 | Down | -0.5134418936 |
| GSE36640 | Down | -0.5714410912 |
| GSE54402 | Down | -0.0020553610 |
| GSE9593 | Up | 0.0893192782 |
| GSE43922 | Up | 0.0125365483 |
| GSE24585 | Up | 1.0524156855 |
| GSE37065 | Up | 0.0846556593 |
| GSE28863_A1 | Down | -0.0765561863 |
| GSE28863_A2 | Down | -0.1544804240 |
| GSE28863_A3 | Up | 0.0748881885 |
| GSE28863_A4 | Up | 0.0366669262 |
| GSE48662 | Up | 0.2260327343 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
