HCSGD entry for SETD1A


1. General information

Official gene symbolSETD1A
Entrez ID9739
Gene full nameSET domain containing 1A
Other gene symbolsKMT2F Set1 Set1A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005694ChromosomeIEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006479Protein methylationIDAbiological_process
GO:0016571Histone methylationIDAbiological_process
GO:0016607Nuclear speckIEAcellular_component
GO:0018022Peptidyl-lysine methylationIDAbiological_process
GO:0018024Histone-lysine N-methyltransferase activityIEAmolecular_function
GO:0034968Histone lysine methylationIDAbiological_process
GO:0035097Histone methyltransferase complexIDAcellular_component
GO:0042800Histone methyltransferase activity (H3-K4 specific)IDAmolecular_function
GO:0048188Set1C/COMPASS complexIDAcellular_component
GO:0051568Histone H3-K4 methylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.59458665700.51854062160.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0292322066
GSE13712_SHEARDown-0.2735731513
GSE13712_STATICDown-0.2459567454
GSE19018Down-0.2780376189
GSE19899_A1Down-0.3062206483
GSE19899_A2Up0.1382225707
PubMed_21979375_A1Down-0.0501956666
PubMed_21979375_A2Up0.2109162578
GSE35957Down-0.3705571941
GSE36640Down-0.0371719504
GSE54402Up0.0991978010
GSE9593Up0.0022147126
GSE43922Up0.1389566738
GSE24585Down-0.2068163863
GSE37065Down-0.0211862995
GSE28863_A1Down-0.0107342363
GSE28863_A2Up0.1070266480
GSE28863_A3Up0.4775670601
GSE28863_A4Up0.0839163626
GSE48662Up0.1479559524

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-760MIMAT0004957MIRT036712CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-3pMIMAT0002891MIRT040819CLASHFunctional MTI (Weak)23622248
hsa-miR-361-5pMIMAT0000703MIRT044067CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044797CLASHFunctional MTI (Weak)23622248
hsa-let-7e-5pMIMAT0000066MIRT051709CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.