HCSGD entry for NR1D1

1. General information

Official gene symbolNR1D1
Entrez ID9572
Gene full namenuclear receptor subfamily 1, group D, member 1
Other gene symbolsEAR1 THRA1 THRAL ear-1 hRev
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIMPbiological_process
GO:0000790Nuclear chromatinIDAcellular_component
GO:0001046Core promoter sequence-specific DNA bindingIDAmolecular_function
GO:0001222Transcription corepressor bindingIDA IMPmolecular_function
GO:0003707Steroid hormone receptor activityIEAmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0004879Ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusISScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005737CytoplasmISScellular_component
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0010467Gene expressionTASbiological_process
GO:0010498Proteasomal protein catabolic processISSbiological_process
GO:0010871Negative regulation of receptor biosynthetic processIMPbiological_process
GO:0019216Regulation of lipid metabolic processISSbiological_process
GO:0020037Heme bindingIDAmolecular_function
GO:0030154Cell differentiationIEAbiological_process
GO:0030425DendriteISScellular_component
GO:0030522Intracellular receptor signaling pathwayTASbiological_process
GO:0034144Negative regulation of toll-like receptor 4 signaling pathwayIMPbiological_process
GO:0035947Regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoterIMPbiological_process
GO:0042752Regulation of circadian rhythmISSbiological_process
GO:0043197Dendritic spineISScellular_component
GO:0044212Transcription regulatory region DNA bindingIDAmolecular_function
GO:0044321Response to leptinISSbiological_process
GO:0045598Regulation of fat cell differentiationISSbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDA IMPbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedISSbiological_process
GO:0060086Circadian temperature homeostasisISSbiological_process
GO:0061178Regulation of insulin secretion involved in cellular response to glucose stimulusISSbiological_process
GO:0061469Regulation of type B pancreatic cell proliferationISSbiological_process
GO:0070859Positive regulation of bile acid biosynthetic processISSbiological_process
GO:0071222Cellular response to lipopolysaccharideIMPbiological_process
GO:2000188Regulation of cholesterol homeostasisISSbiological_process
GO:2000189Positive regulation of cholesterol homeostasisIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08971289080.96695974320.62918545161.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Up0.5159286452
GSE24585Down-0.1147909205
GSE37065Up0.5150224631
GSE28863_A1Up0.1640519229
GSE28863_A2Up0.2486199954
GSE28863_A3Up0.6015038451
GSE28863_A4Down-0.1350410352
GSE48662Up0.0511486129

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017335MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.