HCSGD entry for TAGLN2
1. General information
| Official gene symbol | TAGLN2 |
|---|---|
| Entrez ID | 8407 |
| Gene full name | transgelin 2 |
| Other gene symbols | HA1756 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0007517 | Muscle organ development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4248069564 | 0.0288900802 | 0.9999902473 | 0.3225510178 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3885422794 |
| GSE13712_SHEAR | Down | -0.0192918639 |
| GSE13712_STATIC | Up | 0.2671587659 |
| GSE19018 | Up | 0.4313371821 |
| GSE19899_A1 | Down | -1.0705811055 |
| GSE19899_A2 | Down | -0.2798042020 |
| PubMed_21979375_A1 | Up | 0.1608286045 |
| PubMed_21979375_A2 | Down | -0.9197056303 |
| GSE35957 | Down | -0.4036625955 |
| GSE36640 | Down | -0.9930667114 |
| GSE54402 | Up | 0.4296427579 |
| GSE9593 | Up | 0.0480294037 |
| GSE43922 | Down | -0.0510627569 |
| GSE24585 | Down | -1.0031261172 |
| GSE37065 | Up | 0.2279062245 |
| GSE28863_A1 | Up | 0.0537751094 |
| GSE28863_A2 | Down | -0.0631729676 |
| GSE28863_A3 | Up | 0.1915459567 |
| GSE28863_A4 | Up | 0.0758752286 |
| GSE48662 | Up | 0.2575983558 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT002788 | Luciferase reporter assay | Functional MTI | 20144220 |
| hsa-miR-1 | MIMAT0000416 | MIRT002788 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-1 | MIMAT0000416 | MIRT002788 | pSILAC//Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT002788 | Immunohistochemistry//Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 2130430 |
| hsa-miR-1 | MIMAT0000416 | MIRT002788 | Luciferase reporter assay//Reporter assay;Western blot;qRT-PCR | Functional MTI | 21745735 |
| hsa-miR-1 | MIMAT0000416 | MIRT002788 | Proteomics;Microarray | Non-Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT002788 | Western blot;qRT-PCR;Microarray | Functional MTI | 21701775 |
| hsa-miR-133a-3p | MIMAT0000427 | MIRT005604 | Immunohistochemistry//Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 2130430 |
| hsa-miR-133a-3p | MIMAT0000427 | MIRT005604 | Luciferase reporter assay//Reporter assay;Western blot;qRT-PCR | Functional MTI | 21745735 |
| hsa-miR-133a-3p | MIMAT0000427 | MIRT005604 | Microarray | Functional MTI (Weak) | 21396852 |
| hsa-miR-133a-3p | MIMAT0000427 | MIRT005604 | Western blot;qRT-PCR;Microarray | Functional MTI | 21701775 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038849 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039889 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042618 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3176 | MIMAT0015053 | MIRT052789 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 | |||
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 20144220 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26640786 | RESULTS: Comparison of protein pattern of senescent and young HPMC revealed 29 differentially abundant protein spots, 11 of which were identified to be actin (cytoplasmic 1 and 2), cytokeratin-7, cofilin-2, transgelin-2, Hsp60, Hsc70, proteasome beta-subunits (type-2 and type-3), nucleoside diphosphate kinase A, and cytosolic 5'(3')-deoxyribonucleotidase |
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