HCSGD entry for CALM3

1. General information

Official gene symbolCALM3
Entrez ID808
Gene full namecalmodulin 3 (phosphorylase kinase, delta)
Other gene symbolsPHKD PHKD3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001975Response to amphetamineIEAbiological_process
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0007190Activation of adenylate cyclase activityIEAbiological_process
GO:0008179Adenylate cyclase bindingIEAmolecular_function
GO:0016301Kinase activityIEAmolecular_function
GO:0019722Calcium-mediated signalingIEAbiological_process
GO:0019904Protein domain specific bindingIEAmolecular_function
GO:0030235Nitric-oxide synthase regulator activityIEAmolecular_function
GO:0030426Growth coneIEAcellular_component
GO:0031800Type 3 metabotropic glutamate receptor bindingIEAmolecular_function
GO:0043548Phosphatidylinositol 3-kinase bindingIEAmolecular_function
GO:0044325Ion channel bindingIEAmolecular_function
GO:0047485Protein N-terminus bindingIEAmolecular_function
GO:0048306Calcium-dependent protein bindingIEAmolecular_function
GO:0050998Nitric-oxide synthase bindingIEAmolecular_function
GO:0051000Positive regulation of nitric-oxide synthase activityIEAbiological_process
GO:0051412Response to corticosteroneIEAbiological_process
GO:0060314Regulation of ryanodine-sensitive calcium-release channel activityIEAbiological_process
GO:1901841Regulation of high voltage-gated calcium channel activityIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93671707760.10472964550.99999024730.6208158001

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3382773465
GSE13712_SHEARDown-0.2514400749
GSE13712_STATICUp0.0070269237
GSE19018Up0.1106706243
GSE19899_A1Up0.2262076205
GSE19899_A2Down-0.1989469349
PubMed_21979375_A1Down-0.6575350421
PubMed_21979375_A2Down-0.4028213466
GSE35957Up0.0305388076
GSE36640Down-0.5409269230
GSE54402Down-0.1080200463
GSE9593Down-0.2140194741
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.0982331786
GSE28863_A2Down-0.1142764718
GSE28863_A3Down-0.2435989630
GSE28863_A4Up0.1814764099
GSE48662Up0.0983650673

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NicardipineDB00622 APRD00088
IsofluraneDB00753 APRD00212
LoperamideDB00836 APRD00275
PhenoxybenzamineDB00925 APRD00651
MelatoninDB01065 APRD00742 | DB08189
PimozideDB01100 APRD00218
NifedipineDB01115 APRD00590
BepridilDB01244 APRD00727
CalciumDB01373 -
AprindineDB01429 -
3''-(Beta-Chloroethyl)-2'',4''-Dioxo-3, 5''-Spiro-Oxazolidino-4-Deacetoxy-VinblastineDB02868 EXPT01963
2-Methyl-2-PropanolDB03900 EXPT03021
N-TrimethyllysineDB03977 EXPT02087
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideDB04513 EXPT03246
FlunarizineDB04841 -
(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDEDB08039 -
MYRISTIC ACIDDB08231 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT004467ProteomicsFunctional MTI (Weak)18668040
hsa-miR-7-5pMIMAT0000252MIRT025949MicroarrayFunctional MTI (Weak)19073608
hsa-miR-320aMIMAT0000510MIRT044685CLASHFunctional MTI (Weak)23622248
hsa-miR-27b-3pMIMAT0000419MIRT046170CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.