HCSGD entry for TAC1


1. General information

Official gene symbolTAC1
Entrez ID6863
Gene full nametachykinin, precursor 1
Other gene symbolsHs.2563 NK2 NKNA NPK TAC2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002675Positive regulation of acute inflammatory responseIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006954Inflammatory responseIEAbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIDAbiological_process
GO:0007217Tachykinin receptor signaling pathwayIEAbiological_process
GO:0007218Neuropeptide signaling pathwayIEAbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007268Synaptic transmissionIEAbiological_process
GO:0007320InseminationTASbiological_process
GO:0007616Long-term memoryIEAbiological_process
GO:0008217Regulation of blood pressureIEAbiological_process
GO:0008306Associative learningIEAbiological_process
GO:0009582Detection of abiotic stimulusTASbiological_process
GO:0009725Response to hormoneIEAbiological_process
GO:0010459Negative regulation of heart rateIEAbiological_process
GO:0010634Positive regulation of epithelial cell migrationIEAbiological_process
GO:0019233Sensory perception of painIEAbiological_process
GO:0030424AxonIEAcellular_component
GO:0031835Substance P receptor bindingIEAmolecular_function
GO:0032224Positive regulation of synaptic transmission, cholinergicIEAbiological_process
GO:0032230Positive regulation of synaptic transmission, GABAergicIEAbiological_process
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0035815Positive regulation of renal sodium excretionIEAbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043278Response to morphineIEAbiological_process
GO:0045760Positive regulation of action potentialIEAbiological_process
GO:0045778Positive regulation of ossificationIEAbiological_process
GO:0046878Positive regulation of saliva secretionIEAbiological_process
GO:0048265Response to painIEAbiological_process
GO:0050671Positive regulation of lymphocyte proliferationIEAbiological_process
GO:0051496Positive regulation of stress fiber assemblyIEAbiological_process
GO:2000854Positive regulation of corticosterone secretionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03993894230.87543757840.44865784981.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.6721146689
GSE13712_SHEARUp0.0737590144
GSE13712_STATICUp0.2970452639
GSE19018Down-0.1135510906
GSE19899_A1Up0.1710104498
GSE19899_A2Up0.4330967328
PubMed_21979375_A1Up0.2771930235
PubMed_21979375_A2Down-0.1073599847
GSE35957Up0.0252326480
GSE36640Down-0.0080997501
GSE54402Up1.0994622978
GSE9593Down-0.3291219308
GSE43922Up0.0437303838
GSE24585Up0.1859224335
GSE37065Down-0.0611153767
GSE28863_A1Down-0.1107826598
GSE28863_A2Up0.0026142769
GSE28863_A3Up0.1356864813
GSE28863_A4Down-0.0009896566
GSE48662Down-0.0040668724

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-320aMIMAT0000510MIRT003003Luciferase reporter assayNon-Functional MTI17855557
hsa-miR-206MIMAT0000462MIRT003004Luciferase reporter assay//Reporter assay;OtherFunctional MTI17855557
hsa-miR-130a-3pMIMAT0000425MIRT003005Luciferase reporter assay//Reporter assay;OtherFunctional MTI17855557
hsa-miR-302a-3pMIMAT0000684MIRT020344Reporter assayNon-Functional MTI17855557
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-206MIMAT0000462NAhsa-miR-20617855557
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.