HCSGD entry for SLC6A12

1. General information

Official gene symbolSLC6A12
Entrez ID6539
Gene full namesolute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
Other gene symbolsBGT-1 BGT1 GAT2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005328Neurotransmitter:sodium symporter activityIEAmolecular_function
GO:0005332Gamma-aminobutyric acid:sodium symporter activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006810TransportTASbiological_process
GO:0006811Ion transportTASbiological_process
GO:0006865Amino acid transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007269Neurotransmitter secretionTASbiological_process
GO:0009992Cellular water homeostasisIEAbiological_process
GO:0010033Response to organic substanceIEAbiological_process
GO:0016021Integral component of membraneIEA TAScellular_component
GO:0055085Transmembrane transportTASbiological_process
GO:0071474Cellular hyperosmotic responseIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.51881201700.91706286240.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0716614688
GSE13712_SHEARUp0.0130299373
GSE13712_STATICDown-0.0513403802
GSE19018Down-0.0321750633
GSE19899_A1Up0.1152856036
GSE19899_A2Up0.1757455915
PubMed_21979375_A1Down-0.0422177189
PubMed_21979375_A2Up0.1411721267
GSE35957Up0.1458948381
GSE36640Up0.0466142555
GSE54402Up0.1609541376
GSE9593Down-0.1174531748
GSE43922Up0.0277505958
GSE24585Up0.1167815229
GSE37065Up0.0978856465
GSE28863_A1Down-0.1462934741
GSE28863_A2Down-0.0919466721
GSE28863_A3Up0.3314466373
GSE28863_A4Up0.0591708625
GSE48662Up0.1541629528

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

GuvacineDB08848 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017112MicroarrayFunctional MTI (Weak)18185580
hsa-miR-342-3pMIMAT0000753MIRT043673CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.