HCSGD entry for SKIV2L


1. General information

Official gene symbolSKIV2L
Entrez ID6499
Gene full namesuperkiller viralicidic activity 2-like (S. cerevisiae)
Other gene symbols170A DDX13 HLP SKI2 SKI2W SKIV2 THES2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0004004ATP-dependent RNA helicase activityTASmolecular_function
GO:0004386Helicase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006200ATP catabolic processTASbiological_process
GO:0008026ATP-dependent helicase activityIEAmolecular_function
GO:0008152Metabolic processTASbiological_process
GO:0016818Hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesIEAmolecular_function
GO:0055087Ski complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04916403250.93543112340.48776724461.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0646989425
GSE13712_SHEARUp0.2898304478
GSE13712_STATICDown-0.0405026548
GSE19018Up0.0931119731
GSE19899_A1Up0.2301179444
GSE19899_A2Up0.3963096889
PubMed_21979375_A1Up0.1863512219
PubMed_21979375_A2Up0.5925325860
GSE35957Down-0.4502761510
GSE36640Up0.2789885349
GSE54402Up0.2951378124
GSE9593Down-0.3151596234
GSE43922Up0.3604149940
GSE24585Up0.0770304857
GSE37065Down-0.0254805399
GSE28863_A1Up0.5058483862
GSE28863_A2Up0.7369063773
GSE28863_A3Down-0.1727362931
GSE28863_A4Down-0.2114981463
GSE48662Up0.1417619542

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-222-3pMIMAT0000279MIRT046701CLASHFunctional MTI (Weak)23622248
hsa-let-7e-5pMIMAT0000066MIRT051423CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

24505412In addition, SKI-II reduced cigarette smoke mediated oxidative stress, macrophages and neutrophil infiltration and markers of inflammation in mice
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