HCSGD entry for SH3GL2


1. General information

Official gene symbolSH3GL2
Entrez ID6456
Gene full nameSH3-domain GRB2-like 2
Other gene symbolsCNSA2 EEN-B1 SH3D2A SH3P4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0002090Regulation of receptor internalizationIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006892Post-Golgi vesicle-mediated transportTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0007417Central nervous system developmentTASbiological_process
GO:0008289Lipid bindingIEAmolecular_function
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0030669Clathrin-coated endocytic vesicle membraneTAScellular_component
GO:0042059Negative regulation of epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048488Synaptic vesicle endocytosisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.89540138290.50998065040.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0617406528
GSE13712_SHEARDown-0.1142901057
GSE13712_STATICDown-0.3162879164
GSE19018Down-0.2039651716
GSE19899_A1Up0.0954826651
GSE19899_A2Down-0.0014737223
PubMed_21979375_A1Up0.1516956315
PubMed_21979375_A2Down-0.1505443743
GSE35957Down-0.0012925290
GSE36640Down-0.2014678538
GSE54402Down-0.0478179383
GSE9593Up0.0252174238
GSE43922Up0.0262271140
GSE24585Up0.2211701360
GSE37065Down-0.1991966060
GSE28863_A1Down-0.0533847484
GSE28863_A2Down-0.1154699005
GSE28863_A3Up0.2101765465
GSE28863_A4Up0.0719232364
GSE48662Down-0.0549425851

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-330-3pMIMAT0000751MIRT006922Luciferase reporter assayFunctional MTI23029364
hsa-miR-26b-5pMIMAT0000083MIRT029583MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.