HCSGD entry for ARHGEF28
1. General information
| Official gene symbol | ARHGEF28 |
|---|---|
| Entrez ID | 64283 |
| Gene full name | Rho guanine nucleotide exchange factor (GEF) 28 |
| Other gene symbols | RGNEF RIP2 p190RHOGEF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0021955 | Central nervous system neuron axonogenesis | IEA | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0060052 | Neurofilament cytoskeleton organization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0164798716 | 0.1555605182 | 0.3159262200 | 0.7621022520 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2819292692 |
| GSE13712_SHEAR | Up | 0.4396973617 |
| GSE13712_STATIC | Up | 0.1085418296 |
| GSE19018 | Up | 0.4031187632 |
| GSE19899_A1 | Down | -0.0846029230 |
| GSE19899_A2 | Down | -0.2785768390 |
| PubMed_21979375_A1 | Down | -0.7654222987 |
| PubMed_21979375_A2 | Up | 0.1268229802 |
| GSE35957 | Up | 0.5037772333 |
| GSE36640 | Up | 1.5380635144 |
| GSE54402 | Down | -0.5702188761 |
| GSE9593 | Up | 1.1014690652 |
| GSE43922 | Down | -0.2620649726 |
| GSE24585 | Up | 1.6836520710 |
| GSE37065 | Up | 0.0774194193 |
| GSE28863_A1 | Down | -1.0448658073 |
| GSE28863_A2 | Up | 0.8488578145 |
| GSE28863_A3 | Down | -0.1500141616 |
| GSE28863_A4 | Down | -0.0008752376 |
| GSE48662 | Up | 0.2457388589 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016811 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
