HCSGD entry for SDC2
1. General information
| Official gene symbol | SDC2 |
|---|---|
| Entrez ID | 6383 |
| Gene full name | syndecan 2 |
| Other gene symbols | CD362 HSPG HSPG1 SYND2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001523 | Retinoid metabolic process | TAS | biological_process |
| GO:0001666 | Response to hypoxia | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005796 | Golgi lumen | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006024 | Glycosaminoglycan biosynthetic process | TAS | biological_process |
| GO:0006027 | Glycosaminoglycan catabolic process | TAS | biological_process |
| GO:0007603 | Phototransduction, visible light | TAS | biological_process |
| GO:0008092 | Cytoskeletal protein binding | IEA | molecular_function |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030165 | PDZ domain binding | IPI | molecular_function |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0030203 | Glycosaminoglycan metabolic process | TAS | biological_process |
| GO:0030204 | Chondroitin sulfate metabolic process | TAS | biological_process |
| GO:0031000 | Response to caffeine | IEA | biological_process |
| GO:0042060 | Wound healing | IEA | biological_process |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0043202 | Lysosomal lumen | TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0048813 | Dendrite morphogenesis | IEA | biological_process |
| GO:0048814 | Regulation of dendrite morphogenesis | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9959795942 | 0.0007434786 | 0.9999902473 | 0.0513624672 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.9302155890 |
| GSE13712_SHEAR | Down | -0.4980684499 |
| GSE13712_STATIC | Down | -0.6076124622 |
| GSE19018 | Down | -0.3500574128 |
| GSE19899_A1 | Down | -1.7628538836 |
| GSE19899_A2 | Down | -2.1301397763 |
| PubMed_21979375_A1 | Down | -1.6490270579 |
| PubMed_21979375_A2 | Down | -1.7037021020 |
| GSE35957 | Down | -1.0644917704 |
| GSE36640 | Up | 0.1899084954 |
| GSE54402 | Down | -1.7848414757 |
| GSE9593 | Up | 0.0677756328 |
| GSE43922 | Down | -0.2097119968 |
| GSE24585 | Down | -0.2512858628 |
| GSE37065 | Up | 0.1103173856 |
| GSE28863_A1 | Up | 0.0208139427 |
| GSE28863_A2 | Up | 0.0478506220 |
| GSE28863_A3 | Down | -0.2230186252 |
| GSE28863_A4 | Down | -0.1689020376 |
| GSE48662 | Down | -0.1511052080 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Sargramostim | DB00020 | BTD00035 | BIOD00035 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 19466596 | In this study, we analyzed APRIL and HSPG expression in the colon carcinoma cell line, SW480 by Western blot and RT-PCR |
| 19466596 | And the up-regulation of APRIL and HSPG expression was found in SW480 |
| 19466596 | Furthermore, cellular senescence due to a decreased level of APRIL expression was associated with engagement of HSPG |
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