HCSGD entry for USP47

1. General information

Official gene symbolUSP47
Entrez ID55031
Gene full nameubiquitin specific peptidase 47
Other gene symbolsTRFP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004221Ubiquitin thiolesterase activityIEAmolecular_function
GO:0004843Ubiquitin-specific protease activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0006284Base-excision repairIMPbiological_process
GO:0006511Ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0006974Cellular response to DNA damage stimulusIMPbiological_process
GO:0008234Cysteine-type peptidase activityIEAmolecular_function
GO:0010972Negative regulation of G2/M transition of mitotic cell cycleIMPbiological_process
GO:0019005SCF ubiquitin ligase complexIDAcellular_component
GO:0030307Positive regulation of cell growthIMPbiological_process
GO:0034644Cellular response to UVISSbiological_process
GO:0035520Monoubiquitinated protein deubiquitinationIDAbiological_process
GO:0042493Response to drugIMPbiological_process
GO:0043066Negative regulation of apoptotic processIMPbiological_process
GO:0043154Negative regulation of cysteine-type endopeptidase activity involved in apoptotic processIMPbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIMPbiological_process
GO:0071987WD40-repeat domain bindingIPImolecular_function
GO:1902230Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damageIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.34938598080.26720508340.99999024730.9890435137

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0519983256
GSE13712_SHEARDown-0.0420717319
GSE13712_STATICUp0.0091815352
GSE19018Up0.2364157131
GSE19899_A1Down-0.2452701885
GSE19899_A2Down-0.5363000789
PubMed_21979375_A1Down-0.6667269961
PubMed_21979375_A2Up0.0817708083
GSE35957Up0.2046089522
GSE36640Up0.1127659379
GSE54402Down-0.6181229049
GSE9593Up0.2526024362
GSE43922Down-0.0225583276
GSE24585Up0.3610144831
GSE37065Up0.0110511716
GSE28863_A1Up0.5672381480
GSE28863_A2Up0.8328565838
GSE28863_A3Down-0.6111590822
GSE28863_A4Down-0.0552895182
GSE48662Down-0.0239617486

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022888MicroarrayFunctional MTI (Weak)18668037
hsa-miR-34a-5pMIMAT0000255MIRT025520ProteomicsFunctional MTI (Weak)21566225
hsa-miR-21-5pMIMAT0000076MIRT030994MicroarrayFunctional MTI (Weak)18591254
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.