HCSGD entry for SEPT4

1. General information

Official gene symbolSEPT4
Entrez ID5414
Gene full nameseptin 4
Other gene symbolsARTS BRADEION CE5B3 H5 MART PNUTL2 SEP4 hCDCREL-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000910CytokinesisTASbiological_process
GO:0003924GTPase activityTASmolecular_function
GO:0005198Structural molecule activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005634NucleusIDA NAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005739MitochondrionNAScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0006184GTP catabolic processTASbiological_process
GO:0006915Apoptotic processNASbiological_process
GO:0007049Cell cycleIEAbiological_process
GO:0007420Brain developmentIEAbiological_process
GO:0008152Metabolic processTASbiological_process
GO:0030382Sperm mitochondrion organizationIEAbiological_process
GO:0031105Septin complexIEAcellular_component
GO:0031398Positive regulation of protein ubiquitinationIDAbiological_process
GO:0031514Motile ciliumIEAcellular_component
GO:0042981Regulation of apoptotic processNASbiological_process
GO:0043065Positive regulation of apoptotic processIDAbiological_process
GO:0048240Sperm capacitationIEAbiological_process
GO:2001244Positive regulation of intrinsic apoptotic signaling pathwayIMPbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87186521410.43898740930.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0050586073
GSE13712_SHEARDown-0.1001083046
GSE13712_STATICDown-0.2038756700
GSE19018Up0.0468413013
GSE19899_A1Down-0.0309087085
GSE19899_A2Up0.0148138001
PubMed_21979375_A1Up0.0392067163
PubMed_21979375_A2Up0.0178690129
GSE35957Up0.1040854660
GSE36640Down-0.1174004681
GSE54402Down-0.0679205877
GSE9593Down-0.1350176194
GSE43922Up0.0274822011
GSE24585Up0.2562362560
GSE37065Down-0.2663415095
GSE28863_A1Down-0.2330489476
GSE28863_A2Down-0.3331865349
GSE28863_A3Up0.1888177595
GSE28863_A4Up0.2090556792
GSE48662Up0.0986733989

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017716MicroarrayFunctional MTI (Weak)18185580
hsa-let-7b-5pMIMAT0000063MIRT032353ProteomicsFunctional MTI (Weak)18668040
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.