HCSGD entry for PLA2G5


1. General information

Official gene symbolPLA2G5
Entrez ID5322
Gene full namephospholipase A2, group V
Other gene symbolsFRFB GV-PLA2 PLA2-10 hVPLA(2)
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006644Phospholipid metabolic processTASbiological_process
GO:0006654Phosphatidic acid biosynthetic processTASbiological_process
GO:0006663Platelet activating factor biosynthetic processIEAbiological_process
GO:0008201Heparin bindingIEAmolecular_function
GO:0009986Cell surfaceIEAcellular_component
GO:0016042Lipid catabolic processIEAbiological_process
GO:0019370Leukotriene biosynthetic processIEAbiological_process
GO:0034097Response to cytokineIEAbiological_process
GO:0036148Phosphatidylglycerol acyl-chain remodelingTASbiological_process
GO:0036149Phosphatidylinositol acyl-chain remodelingTASbiological_process
GO:0036150Phosphatidylserine acyl-chain remodelingTASbiological_process
GO:0036151Phosphatidylcholine acyl-chain remodelingTASbiological_process
GO:0036152Phosphatidylethanolamine acyl-chain remodelingTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046474Glycerophospholipid biosynthetic processTASbiological_process
GO:0047498Calcium-dependent phospholipase A2 activityIEAmolecular_function
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0050482Arachidonic acid secretionIEAbiological_process
GO:0051591Response to cAMPIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.68351631400.14439534210.99999024730.7317346554

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.6064326785
GSE13712_SHEARUp0.0229437433
GSE13712_STATICDown-0.1170584525
GSE19018Up0.0819978900
GSE19899_A1Up0.0929225076
GSE19899_A2Up0.0084427262
PubMed_21979375_A1Down-0.1547200008
PubMed_21979375_A2Down-0.0006026618
GSE35957Down-1.0491383273
GSE36640Up0.0494107810
GSE54402Up0.0186250531
GSE9593Up0.0349533053
GSE43922Down-0.0299500716
GSE24585Down-0.0370844334
GSE37065Down-0.8318017760
GSE28863_A1Up0.3295356103
GSE28863_A2Up0.0070989217
GSE28863_A3Up0.0178057125
GSE28863_A4Up0.2760696414
GSE48662Down-0.2121207962

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-128-3pMIMAT0000424MIRT021933MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.