HCSGD entry for TDP2

1. General information

Official gene symbolTDP2
Entrez ID51567
Gene full nametyrosyl-DNA phosphodiesterase 2
Other gene symbolsAD022 EAP2 EAPII TTRAP dJ30M3.3 hTDP2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingIDA TASmolecular_function
GO:0003697Single-stranded DNA bindingIDAmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0004518Nuclease activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006302Double-strand break repairIDA IMPbiological_process
GO:0007166Cell surface receptor signaling pathwayTASbiological_process
GO:0016605PML bodyIDAcellular_component
GO:0030145Manganese ion bindingIDAmolecular_function
GO:0036317Tyrosyl-RNA phosphodiesterase activityIDAmolecular_function
GO:00702605'-tyrosyl-DNA phosphodiesterase activityIDA IMPmolecular_function
GO:2001141Regulation of RNA biosynthetic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02976010410.93031613920.39944706781.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.1008780456
GSE13712_SHEARUp0.3826772838
GSE13712_STATICUp0.3380824814
GSE19018Up0.0602464134
GSE19899_A1Up0.0392022070
GSE19899_A2Down-0.1476162053
PubMed_21979375_A1Up0.7525222699
PubMed_21979375_A2Down-0.0131267140
GSE35957Up0.3752873406
GSE36640Down-0.1623658921
GSE54402Up0.3530865479
GSE9593Up0.6856244832
GSE43922Down-0.0380866439
GSE24585Up0.2535755570
GSE37065Up0.7621893109
GSE28863_A1Up0.0002053161
GSE28863_A2Up0.4032258268
GSE28863_A3Down-0.3655597544
GSE28863_A4Down-0.0864167316
GSE48662Down-0.1853196812

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.