HCSGD entry for ATF1

1. General information

Official gene symbolATF1
Entrez ID466
Gene full nameactivating transcription factor 1
Other gene symbolsEWS-ATF1 FUS/ATF-1 TREB36
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002224Toll-like receptor signaling pathwayTASbiological_process
GO:0002755MyD88-dependent toll-like receptor signaling pathwayTASbiological_process
GO:0002756MyD88-independent toll-like receptor signaling pathwayTASbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005667Transcription factor complexIEAcellular_component
GO:0010976Positive regulation of neuron projection developmentIEAbiological_process
GO:0014070Response to organic cyclic compoundIEAbiological_process
GO:0032025Response to cobalt ionIEAbiological_process
GO:0032403Protein complex bindingIEAmolecular_function
GO:0034134Toll-like receptor 2 signaling pathwayTASbiological_process
GO:0034138Toll-like receptor 3 signaling pathwayTASbiological_process
GO:0034142Toll-like receptor 4 signaling pathwayTASbiological_process
GO:0034146Toll-like receptor 5 signaling pathwayTASbiological_process
GO:0034162Toll-like receptor 9 signaling pathwayTASbiological_process
GO:0034166Toll-like receptor 10 signaling pathwayTASbiological_process
GO:0035666TRIF-dependent toll-like receptor signaling pathwayTASbiological_process
GO:0038123Toll-like receptor TLR1:TLR2 signaling pathwayTASbiological_process
GO:0038124Toll-like receptor TLR6:TLR2 signaling pathwayTASbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0043623Cellular protein complex assemblyIEAbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045740Positive regulation of DNA replicationIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0051403Stress-activated MAPK cascadeTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82237876220.05580009120.99999024730.4443915885

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3177020136
GSE13712_SHEARUp0.3003974063
GSE13712_STATICUp0.0552688626
GSE19018Down-0.1868355657
GSE19899_A1Down-0.4965384284
GSE19899_A2Down-0.4540178801
PubMed_21979375_A1Down-0.3138860494
PubMed_21979375_A2Down-0.3541613296
GSE35957Up0.0631287381
GSE36640Down-0.8116269014
GSE54402Down-0.2129997396
GSE9593Down-0.0389830710
GSE43922Down-0.2189525997
GSE24585Up0.4044918968
GSE37065Up0.1167189294
GSE28863_A1Up0.0798074097
GSE28863_A2Up0.1670475530
GSE28863_A3Down-0.6116098748
GSE28863_A4Up0.0007985188
GSE48662Up0.1786101194

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024634MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026443MicroarrayFunctional MTI (Weak)19074876
hsa-miR-23a-5pMIMAT0004496MIRT038958CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.