HCSGD entry for MEF2D

1. General information

Official gene symbolMEF2D
Entrez ID4209
Gene full namemyocyte enhancer factor 2D
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000977RNA polymerase II regulatory region sequence-specific DNA bindingIDAmolecular_function
GO:0000981Sequence-specific DNA binding RNA polymerase II transcription factor activityIDAmolecular_function
GO:0001649Osteoblast differentiationIEAbiological_process
GO:0001958Endochondral ossificationIEAbiological_process
GO:0002062Chondrocyte differentiationIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDAbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0007399Nervous system developmentIEAbiological_process
GO:0007512Adult heart developmentIEPbiological_process
GO:0007517Muscle organ developmentTASbiological_process
GO:0033613Activating transcription factor bindingIPImolecular_function
GO:0035914Skeletal muscle cell differentiationIEAbiological_process
GO:0042826Histone deacetylase bindingIPImolecular_function
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046983Protein dimerization activityIEAmolecular_function
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.05816709850.96023857760.52288804641.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2122421389
GSE13712_SHEARUp0.2208890759
GSE13712_STATICUp0.1455935672
GSE19018Up0.2877032760
GSE19899_A1Up0.0620371321
GSE19899_A2Up0.4886037123
PubMed_21979375_A1Up0.4679396028
PubMed_21979375_A2Up0.6628750309
GSE35957Up0.1469446672
GSE36640Up0.2587416137
GSE54402Up0.1198442356
GSE9593Up0.1342072233
GSE43922Up0.3844046212
GSE24585Up0.2095291750
GSE37065Up0.0151049692
GSE28863_A1Up0.1101302336
GSE28863_A2Up0.3061197930
GSE28863_A3Up0.0075868273
GSE28863_A4Down-0.2696434987
GSE48662Up0.2733716817

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-20a-5pMIMAT0000075MIRT003012Luciferase reporter assayFunctional MTI19666108
hsa-miR-17-5pMIMAT0000070MIRT003015Luciferase reporter assayFunctional MTI19666108
hsa-miR-99a-5pMIMAT0000097MIRT027395SequencingFunctional MTI (Weak)20371350
hsa-miR-26b-5pMIMAT0000083MIRT029852MicroarrayFunctional MTI (Weak)19088304
hsa-miR-19b-3pMIMAT0000074MIRT031251SequencingFunctional MTI (Weak)20371350
hsa-miR-877-5pMIMAT0004949MIRT037248CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044549CLASHFunctional MTI (Weak)23622248
hsa-let-7f-5pMIMAT0000067MIRT051353CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.