HCSGD entry for MCM7


1. General information

Official gene symbolMCM7
Entrez ID4176
Gene full nameminichromosome maintenance complex component 7
Other gene symbolsCDC47 MCM2 P1.1-MCM3 P1CDC47 P85MCM PNAS146
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000785ChromatinTAScellular_component
GO:0003677DNA bindingTASmolecular_function
GO:0003678DNA helicase activityIEAmolecular_function
GO:0003697Single-stranded DNA bindingIEAmolecular_function
GO:0004003ATP-dependent DNA helicase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolIEAcellular_component
GO:0006200ATP catabolic processIDAbiological_process
GO:0006260DNA replicationTASbiological_process
GO:0006268DNA unwinding involved in DNA replicationIEAbiological_process
GO:0006270DNA replication initiationIEAbiological_process
GO:0006271DNA strand elongation involved in DNA replicationTASbiological_process
GO:0006974Cellular response to DNA damage stimulusIMPbiological_process
GO:0008283Cell proliferationIEAbiological_process
GO:0042325Regulation of phosphorylationIMPbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0042555MCM complexIDA IEA IMPcellular_component
GO:0071364Cellular response to epidermal growth factor stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93978952930.00049663390.99999024730.0411066038

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.4172553378
GSE13712_SHEARDown-0.2174532468
GSE13712_STATICDown-0.2673391252
GSE19018Down-0.2803890202
GSE19899_A1Down-1.4011312825
GSE19899_A2Down-2.7279444424
PubMed_21979375_A1Down-0.9917121466
PubMed_21979375_A2Down-2.7591840786
GSE35957Down-2.4552642889
GSE36640Down-3.3078953396
GSE54402Down-0.0595500868
GSE9593Down-1.7725149331
GSE43922Down-0.7104974043
GSE24585Up0.0536317554
GSE37065Down-0.4623845459
GSE28863_A1Up0.3154645837
GSE28863_A2Up0.6938825282
GSE28863_A3Up0.3219414060
GSE28863_A4Down-0.0940934024
GSE48662Down-0.5384270899

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT016521ProteomicsFunctional MTI (Weak)21512034
hsa-miR-193b-3pMIMAT0002819MIRT016521MicroarrayFunctional MTI (Weak)20304954
hsa-miR-124-3pMIMAT0000422MIRT022853Proteomics;MicroarrayNon-Functional MTI (Weak)18668037
hsa-miR-1MIMAT0000416MIRT023890ProteomicsFunctional MTI (Weak)18668040
hsa-miR-34a-5pMIMAT0000255MIRT025469ProteomicsFunctional MTI (Weak)21566225
hsa-miR-1914-5pMIMAT0007889MIRT035789CLASHFunctional MTI (Weak)23622248
hsa-miR-93-3pMIMAT0004509MIRT038750CLASHFunctional MTI (Weak)23622248
hsa-miR-503-5pMIMAT0002874MIRT041105CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT042002CLASHFunctional MTI (Weak)23622248
hsa-miR-222-3pMIMAT0000279MIRT046710CLASHFunctional MTI (Weak)23622248
hsa-miR-197-3pMIMAT0000227MIRT048095CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049815CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052320CLASHFunctional MTI (Weak)23622248
hsa-miR-1260bMIMAT0015041MIRT052674CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.