HCSGD entry for LLGL1

1. General information

Official gene symbolLLGL1
Entrez ID3996
Gene full namelethal giant larvae homolog 1 (Drosophila)
Other gene symbolsDLG4 HUGL HUGL-1 HUGL1 LLGL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000137Golgi cis cisternaISScellular_component
GO:0000139Golgi membraneIEAcellular_component
GO:0005097Rab GTPase activator activityISSmolecular_function
GO:0005198Structural molecule activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005856CytoskeletonTAScellular_component
GO:0006461Protein complex assemblyIDAbiological_process
GO:0006887ExocytosisIEAbiological_process
GO:0006893Golgi to plasma membrane transportISSbiological_process
GO:0007409AxonogenesisISSbiological_process
GO:0019901Protein kinase bindingIDAmolecular_function
GO:0030424AxonISScellular_component
GO:0030864Cortical actin cytoskeletonIDAcellular_component
GO:0030866Cortical actin cytoskeleton organizationIDAbiological_process
GO:0031901Early endosome membraneISScellular_component
GO:0032320Positive regulation of Ras GTPase activityISSbiological_process
GO:0032588Trans-Golgi network membraneISScellular_component
GO:0032851Positive regulation of Rab GTPase activityISSbiological_process
GO:0035090Maintenance of apical/basal cell polarityIEAbiological_process
GO:0035748Myelin sheath abaxonal regionIEAcellular_component
GO:0043085Positive regulation of catalytic activityISSbiological_process
GO:0043547Positive regulation of GTPase activityISSbiological_process
GO:0050790Regulation of catalytic activityISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97276761140.08932127580.99999024730.5667852700

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0866958315
GSE13712_SHEARDown-0.4476028984
GSE13712_STATICDown-0.3668033638
GSE19018Up0.1155812720
GSE19899_A1Up0.0340242492
GSE19899_A2Down-0.1196597968
PubMed_21979375_A1Down-0.4971818798
PubMed_21979375_A2Down-0.2221867577
GSE35957Up0.1160130691
GSE36640Down-0.1765611970
GSE54402Down-0.0486671120
GSE9593Up0.0850276213
GSE43922Down-0.1066128990
GSE24585Down-0.1458934640
GSE37065Down-0.0723485828
GSE28863_A1Up0.1445237597
GSE28863_A2Down-0.1372815613
GSE28863_A3Down-0.5058764412
GSE28863_A4Down-0.1659190052
GSE48662Up0.0313480643

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-196a-5pMIMAT0000226MIRT026101qRT-PCRFunctional MTI (Weak)21077158
hsa-miR-24-3pMIMAT0000080MIRT030531MicroarrayFunctional MTI (Weak)19748357
hsa-miR-186-5pMIMAT0000456MIRT045222CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.