HCSGD entry for ARHGAP6

1. General information

Official gene symbolARHGAP6
Entrez ID395
Gene full nameRho GTPase activating protein 6
Other gene symbolsRHOGAP6 RHOGAPX-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005070SH3/SH2 adaptor activityTASmolecular_function
GO:0005100Rho GTPase activator activityISSmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005737CytoplasmIMPcellular_component
GO:0005829CytosolTAScellular_component
GO:0005884Actin filamentNAScellular_component
GO:0007165Signal transductionIEAbiological_process
GO:0007202Activation of phospholipase C activityIDAbiological_process
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0007266Rho protein signal transductionNASbiological_process
GO:0009967Positive regulation of signal transductionTASbiological_process
GO:0010518Positive regulation of phospholipase activityIDAbiological_process
GO:0015629Actin cytoskeletonISScellular_component
GO:0016004Phospholipase activator activityIDAmolecular_function
GO:0017124SH3 domain bindingIEAmolecular_function
GO:0030041Actin filament polymerizationNASbiological_process
GO:0043087Regulation of GTPase activityISSbiological_process
GO:0043274Phospholipase bindingIPImolecular_function
GO:0048041Focal adhesion assemblyIEAbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0051497Negative regulation of stress fiber assemblyIMPbiological_process
GO:0051895Negative regulation of focal adhesion assemblyIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02181577450.80987025190.35505461251.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0727113766
GSE13712_SHEARDown-0.2345898944
GSE13712_STATICDown-0.2655031642
GSE19018Down-0.2980365589
GSE19899_A1Up0.6766662201
GSE19899_A2Up0.7228766935
PubMed_21979375_A1Up0.9938950325
PubMed_21979375_A2Up2.0585409149
GSE35957Up0.4183696264
GSE36640Up0.7155352698
GSE54402Down-0.2307619112
GSE9593Down-0.2369691764
GSE43922Up0.5441663921
GSE24585Up0.2523222969
GSE37065Up0.3152583597
GSE28863_A1Up0.0677805901
GSE28863_A2Down-0.1337472653
GSE28863_A3Up0.2388525771
GSE28863_A4Up0.0041693332
GSE48662Down-0.1630246452

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.