HCSGD entry for JAG2

1. General information

Official gene symbolJAG2
Entrez ID3714
Gene full namejagged 2
Other gene symbolsHJ2 SER2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001501Skeletal system developmentIEAbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0003016Respiratory system processIEAbiological_process
GO:0005112Notch bindingIPImolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneISScellular_component
GO:0007049Cell cycleNASbiological_process
GO:0007219Notch signaling pathwayNAS TASbiological_process
GO:0007220Notch receptor processingTASbiological_process
GO:0007283SpermatogenesisIEPbiological_process
GO:0008083Growth factor activityIDAmolecular_function
GO:0009912Auditory receptor cell fate commitmentISSbiological_process
GO:0016331Morphogenesis of embryonic epitheliumIEAbiological_process
GO:0030154Cell differentiationIDAbiological_process
GO:0030155Regulation of cell adhesionIEAbiological_process
GO:0030217T cell differentiationIDAbiological_process
GO:0030334Regulation of cell migrationNASbiological_process
GO:0042127Regulation of cell proliferationIDAbiological_process
GO:0042475Odontogenesis of dentin-containing toothIEAbiological_process
GO:0042492Gamma-delta T cell differentiationIEAbiological_process
GO:0045061Thymic T cell selectionIDAbiological_process
GO:1990134Epithelial cell apoptotic process involved in palatal shelf morphogenesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.17323556860.36793623340.81746972581.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0140947721
GSE13712_SHEARDown-1.0697158911
GSE13712_STATICDown-0.6428562780
GSE19018Up0.1034551864
GSE19899_A1Up0.2325883759
GSE19899_A2Up0.9679090074
PubMed_21979375_A1Up0.6391319203
PubMed_21979375_A2Up0.8099216191
GSE35957Down-0.0208465668
GSE36640Up0.4465794133
GSE54402Up0.1125796713
GSE9593Up0.0902816632
GSE43922Up0.3564027357
GSE24585Down-0.2764233039
GSE37065Down-0.0457153581
GSE28863_A1Down-0.1233359896
GSE28863_A2Down-0.3746462795
GSE28863_A3Down-0.1437874283
GSE28863_A4Down-0.0145021962
GSE48662Up0.0330117985

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT016805MicroarrayFunctional MTI (Weak)18185580
hsa-miR-124-3pMIMAT0000422MIRT022161MicroarrayFunctional MTI (Weak)18668037
hsa-miR-484MIMAT0002174MIRT042161CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049515CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.