HCSGD entry for IDH3A


1. General information

Official gene symbolIDH3A
Entrez ID3419
Gene full nameisocitrate dehydrogenase 3 (NAD+) alpha
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingIEAmolecular_function
GO:0004449Isocitrate dehydrogenase (NAD+) activityIEAmolecular_function
GO:0005739MitochondrionIDAcellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0005975Carbohydrate metabolic processNASbiological_process
GO:0006099Tricarboxylic acid cycleTASbiological_process
GO:0016616Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorIEAmolecular_function
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0051287NAD bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06023586110.57802199000.53203627521.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3537784986
GSE13712_SHEARUp0.1541639494
GSE13712_STATICUp0.0685059506
GSE19018Down-0.5611208431
GSE19899_A1Up0.3250688148
GSE19899_A2Up0.3528116804
PubMed_21979375_A1Up0.3059561570
PubMed_21979375_A2Up0.4338253186
GSE35957Up0.2688949488
GSE36640Up0.4118790794
GSE54402Up0.3458451769
GSE9593Down-0.3260815843
GSE43922Up0.2934587066
GSE24585Up0.0419971674
GSE37065Up0.0765796706
GSE28863_A1Down-0.4000013868
GSE28863_A2Down-0.0121596529
GSE28863_A3Down-0.4929971098
GSE28863_A4Up0.4401871795
GSE48662Down-0.4173035846

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT031744ProteomicsFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.