HCSGD entry for HSD17B1
1. General information
| Official gene symbol | HSD17B1 |
|---|---|
| Entrez ID | 3292 |
| Gene full name | hydroxysteroid (17-beta) dehydrogenase 1 |
| Other gene symbols | EDH17B2 EDHB17 HSD17 SDR28C1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | TAS | molecular_function |
| GO:0004303 | Estradiol 17-beta-dehydrogenase activity | TAS | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006694 | Steroid biosynthetic process | TAS | biological_process |
| GO:0006703 | Estrogen biosynthetic process | IEA TAS | biological_process |
| GO:0008202 | Steroid metabolic process | TAS | biological_process |
| GO:0008210 | Estrogen metabolic process | TAS | biological_process |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0060348 | Bone development | IEA | biological_process |
| GO:0061370 | Testosterone biosynthetic process | IEA | biological_process |
| GO:0071248 | Cellular response to metal ion | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4608795259 | 0.6403682953 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2098826117 |
| GSE13712_SHEAR | Down | -0.1159109117 |
| GSE13712_STATIC | Up | 0.0024081387 |
| GSE19018 | Up | 0.0477842156 |
| GSE19899_A1 | Down | -0.0640294617 |
| GSE19899_A2 | Up | 0.7563844342 |
| PubMed_21979375_A1 | Down | -0.2312787660 |
| PubMed_21979375_A2 | Up | 0.2592026187 |
| GSE35957 | Up | 0.0032874003 |
| GSE36640 | Up | 0.0687885193 |
| GSE54402 | Up | 0.1931516824 |
| GSE9593 | Down | -0.2013920201 |
| GSE43922 | Up | 0.0455206943 |
| GSE24585 | Up | 0.0083506200 |
| GSE37065 | Down | -0.0968718826 |
| GSE28863_A1 | Down | -0.0066929568 |
| GSE28863_A2 | Down | -0.0438806116 |
| GSE28863_A3 | Up | 0.1776753611 |
| GSE28863_A4 | Down | -0.0348682477 |
| GSE48662 | Up | 0.2078131016 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
| 4-Androstenedione | DB01536 | EXPT00569 | DB07386 |
| Androstanedione | DB01561 | DB03620 |
| Dehydroepiandrosterone | DB01708 | EXPT00519 | DB06593 |
| Equilin | DB02187 | EXPT01355 |
| EM-1745 | DB02323 | EXPT01802 |
| 2'-Monophosphoadenosine 5'-Diphosphoribose | DB03461 | EXPT02293 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
