HCSGD entry for HHEX

1. General information

Official gene symbolHHEX
Entrez ID3087
Gene full namehematopoietically expressed homeobox
Other gene symbolsHEX HMPH HOX11L-PEN PRH PRHX
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDA IEAbiological_process
GO:0001570VasculogenesisIEAbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0002573Myeloid leukocyte differentiationIEAbiological_process
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005737CytoplasmIDA IEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006406MRNA export from nucleusIDAbiological_process
GO:0007165Signal transductionIEAbiological_process
GO:0007492Endoderm developmentIEAbiological_process
GO:0008134Transcription factor bindingIPImolecular_function
GO:0008190Eukaryotic initiation factor 4E bindingIDAmolecular_function
GO:0008283Cell proliferationIDAbiological_process
GO:0008301DNA binding, bendingIDAmolecular_function
GO:0009611Response to woundingIEAbiological_process
GO:0009952Anterior/posterior pattern specificationISSbiological_process
GO:0010621Negative regulation of transcription by transcription factor localizationICbiological_process
GO:0010944Negative regulation of transcription by competitive promoter bindingTASbiological_process
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0016525Negative regulation of angiogenesisIEA ISSbiological_process
GO:0016973Poly(A)+ mRNA export from nucleusIMPbiological_process
GO:0017025TBP-class protein bindingTASmolecular_function
GO:0022027Interkinetic nuclear migrationIEAbiological_process
GO:0030154Cell differentiationICbiological_process
GO:0030177Positive regulation of Wnt signaling pathwayIEA ISSbiological_process
GO:0030183B cell differentiationIEA ISSbiological_process
GO:0030878Thyroid gland developmentIEAbiological_process
GO:0030948Negative regulation of vascular endothelial growth factor receptor signaling pathwayIEA ISSbiological_process
GO:0031016Pancreas developmentIEAbiological_process
GO:0032993Protein-DNA complexIDAcellular_component
GO:0034504Protein localization to nucleusIDAbiological_process
GO:0035050Embryonic heart tube developmentIEAbiological_process
GO:0035264Multicellular organism growthIEAbiological_process
GO:0042127Regulation of cell proliferationIEAbiological_process
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0043434Response to peptide hormoneIEAbiological_process
GO:0043565Sequence-specific DNA bindingIDA IEAmolecular_function
GO:0044212Transcription regulatory region DNA bindingIDA TASmolecular_function
GO:0045736Negative regulation of cyclin-dependent protein serine/threonine kinase activityIDAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0048853Forebrain morphogenesisIEAbiological_process
GO:0060431Primary lung bud formationIEAbiological_process
GO:0061009Common bile duct developmentIEAbiological_process
GO:0061010Gall bladder developmentIEAbiological_process
GO:0061011Hepatic duct developmentIEAbiological_process
GO:0061017Hepatoblast differentiationIEAbiological_process
GO:0070365Hepatocyte differentiationIEAbiological_process
GO:0070491Repressing transcription factor bindingIDAmolecular_function
GO:0071103DNA conformation changeIDAbiological_process
GO:0071837HMG box domain bindingIEAmolecular_function
GO:0090009Primitive streak formationIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.78874686750.00688344670.99999024730.1653088342

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.0954575419
GSE13712_SHEARUp0.0644126254
GSE13712_STATICDown-0.1363708124
GSE19018Down-0.4854562572
GSE19899_A1Down-1.4608138481
GSE19899_A2Down-2.6668514457
PubMed_21979375_A1Down-2.4900665346
PubMed_21979375_A2Down-3.2232734652
GSE35957Down-0.4106450104
GSE36640Up0.8747719385
GSE54402Up0.0909362830
GSE9593Down-0.1735350930
GSE43922Down-0.3871761884
GSE24585Down-0.2719817265
GSE37065Up0.0050230142
GSE28863_A1Down-0.1699693574
GSE28863_A2Down-0.0588729726
GSE28863_A3Up0.2654807860
GSE28863_A4Up0.0289571787
GSE48662Down-0.4426040033

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-130b-3pMIMAT0000691MIRT020132SequencingFunctional MTI (Weak)20371350
hsa-miR-19b-3pMIMAT0000074MIRT031099SequencingFunctional MTI (Weak)20371350
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.