HCSGD entry for BLOC1S6

1. General information

Official gene symbolBLOC1S6
Entrez ID26258
Gene full namebiogenesis of lysosomal organelles complex-1, subunit 6, pallidin
Other gene symbolsBLOS6 HPS9 PA PALLID PLDN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005768EndosomeIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006892Post-Golgi vesicle-mediated transportTASbiological_process
GO:0007596Blood coagulationIEAbiological_process
GO:0008089Anterograde axon cargo transportIEA ISSbiological_process
GO:0012505Endomembrane systemIEAcellular_component
GO:0016081Synaptic vesicle docking involved in exocytosisNASbiological_process
GO:0019898Extrinsic component of membraneIDAcellular_component
GO:0019905Syntaxin bindingTASmolecular_function
GO:0030133Transport vesicleIDAcellular_component
GO:0030318Melanocyte differentiationIEAbiological_process
GO:0031083BLOC-1 complexIDAcellular_component
GO:0031175Neuron projection developmentIEA ISSbiological_process
GO:0031201SNARE complexIDAcellular_component
GO:0032402Melanosome transportIDAbiological_process
GO:0032438Melanosome organizationNASbiological_process
GO:0032816Positive regulation of natural killer cell activationIEAbiological_process
GO:0033299Secretion of lysosomal enzymesIEAbiological_process
GO:0035646Endosome to melanosome transportIDAbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0042803Protein homodimerization activityIDA IPImolecular_function
GO:0048490Anterograde synaptic vesicle transportIEA ISSbiological_process
GO:0050942Positive regulation of pigment cell differentiationIDAbiological_process
GO:0051015Actin filament bindingIDAmolecular_function
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.84548614030.21408428630.99999024730.8933971623

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0823728092
GSE13712_SHEARUp0.0294468459
GSE13712_STATICDown-0.0064461853
GSE19018Up0.1992348335
GSE19899_A1Down-0.3287992837
GSE19899_A2Down-0.3979070679
PubMed_21979375_A1Down-0.3378658366
PubMed_21979375_A2Down-0.2047782756
GSE35957Up0.1485188091
GSE36640Down-0.0492140737
GSE54402Up0.0379375234
GSE9593Up0.3241329621
GSE43922Down-0.2834811606
GSE24585Down-0.0286403714
GSE37065Up0.0828889849
GSE28863_A1Down-0.2690761331
GSE28863_A2Up0.0776852214
GSE28863_A3Down-0.5019151212
GSE28863_A4Up0.2342704807
GSE48662Down-0.1934875893

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT002614MicroarrayFunctional MTI (Weak)18668037
hsa-miR-124-3pMIMAT0000422MIRT002614MicroarrayFunctional MTI (Weak)15685193
hsa-miR-30b-5pMIMAT0000420MIRT023412SequencingFunctional MTI (Weak)20371350
hsa-miR-101-3pMIMAT0000099MIRT027360SequencingFunctional MTI (Weak)20371350
hsa-miR-484MIMAT0002174MIRT042100CLASHFunctional MTI (Weak)23622248
hsa-miR-3176MIMAT0015053MIRT052798CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.