HCSGD entry for GAD1

1. General information

Official gene symbolGAD1
Entrez ID2571
Gene full nameglutamate decarboxylase 1 (brain, 67kDa)
Other gene symbolsCPSQ1 GAD SCP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004351Glutamate decarboxylase activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIDAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005938Cell cortexIEAcellular_component
GO:0006538Glutamate catabolic processTASbiological_process
GO:0006540Glutamate decarboxylation to succinateTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007269Neurotransmitter secretionTASbiological_process
GO:0009449Gamma-aminobutyric acid biosynthetic processIEAbiological_process
GO:0012506Vesicle membraneNAScellular_component
GO:0016595Glutamate bindingIEAmolecular_function
GO:0016831Carboxy-lyase activityIEAmolecular_function
GO:0018352Protein-pyridoxal-5-phosphate linkageTASbiological_process
GO:0019752Carboxylic acid metabolic processIEAbiological_process
GO:0030170Pyridoxal phosphate bindingIEAmolecular_function
GO:0042136Neurotransmitter biosynthetic processIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0043679Axon terminusIEAcellular_component
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0047485Protein N-terminus bindingIEAmolecular_function
GO:0048786Presynaptic active zoneIEAcellular_component
GO:0061202Clathrin-sculpted gamma-aminobutyric acid transport vesicle membraneTAScellular_component
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.44059963150.55772318680.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4167962591
GSE13712_SHEARDown-0.0774748393
GSE13712_STATICUp0.0266783988
GSE19018Up0.0896697229
GSE19899_A1Up0.1907917870
GSE19899_A2Up0.1510731877
PubMed_21979375_A1Up0.3867650624
PubMed_21979375_A2Up0.2815043425
GSE35957Up0.0307574191
GSE36640Up0.2418183507
GSE54402Up0.1017804203
GSE9593Up0.0462540274
GSE43922Up0.0133824986
GSE24585Down-0.3746550413
GSE37065Down-0.2990276167
GSE28863_A1Down-0.3806288986
GSE28863_A2Up0.4190911144
GSE28863_A3Down-0.4787427940
GSE28863_A4Down-0.0272845350
GSE48662Down-0.1153918108

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.