HCSGD entry for GABPA

1. General information

Official gene symbolGABPA
Entrez ID2551
Gene full nameGA binding protein transcription factor, alpha subunit 60kDa
Other gene symbolsE4TF1-60 E4TF1A NFT2 NRF2 NRF2A RCH04A07
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0000790Nuclear chromatinIDAcellular_component
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingIDAmolecular_function
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionIDAmolecular_function
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0003677DNA bindingTASmolecular_function
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0003713Transcription coactivator activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0044212Transcription regulatory region DNA bindingIDAmolecular_function
GO:0045653Negative regulation of megakaryocyte differentiationIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046982Protein heterodimerization activityIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.05651654190.67828758790.51620891741.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0857147168
GSE13712_SHEARUp0.2476349060
GSE13712_STATICDown-0.1577753891
GSE19018Down-0.1080192577
GSE19899_A1Up0.6967844986
GSE19899_A2Up0.4903398056
PubMed_21979375_A1Up1.4353613436
PubMed_21979375_A2Up1.3598952361
GSE35957Up0.1544953024
GSE36640Down-0.2169057970
GSE54402Up0.3777139914
GSE9593Down-0.2989482369
GSE43922Up0.4647314656
GSE24585Down-0.1018138911
GSE37065Up0.0084095487
GSE28863_A1Down-0.1461121253
GSE28863_A2Down-0.0647153450
GSE28863_A3Down-0.0352310879
GSE28863_A4Up0.0660991279
GSE48662Down-0.4572749122

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-18a-5pMIMAT0000072MIRT031329SequencingFunctional MTI (Weak)20371350
hsa-miR-92a-3pMIMAT0000092MIRT048948CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.