HCSGD entry for ACSL6

1. General information

Official gene symbolACSL6
Entrez ID23305
Gene full nameacyl-CoA synthetase long-chain family member 6
Other gene symbolsACS2 FACL6 LACS 6 LACS2 LACS5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001666Response to hypoxiaIEAbiological_process
GO:0001676Long-chain fatty acid metabolic processIDAbiological_process
GO:0003824Catalytic activityIEAmolecular_function
GO:0004467Long-chain fatty acid-CoA ligase activityIDA IEA NASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0005741Mitochondrial outer membraneIEAcellular_component
GO:0005778Peroxisomal membraneIEAcellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0005886Plasma membraneNAScellular_component
GO:0006637Acyl-CoA metabolic processNASbiological_process
GO:0006641Triglyceride metabolic processIEAbiological_process
GO:0007405Neuroblast proliferationIEAbiological_process
GO:0007584Response to nutrientIEAbiological_process
GO:0008654Phospholipid biosynthetic processIEAbiological_process
GO:0009629Response to gravityIEAbiological_process
GO:0010747Positive regulation of plasma membrane long-chain fatty acid transportIEAbiological_process
GO:0010867Positive regulation of triglyceride biosynthetic processIEAbiological_process
GO:0010976Positive regulation of neuron projection developmentIEAbiological_process
GO:0015908Fatty acid transportIEAbiological_process
GO:0016020MembraneIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0019432Triglyceride biosynthetic processTASbiological_process
GO:0019899Enzyme bindingIPImolecular_function
GO:0032869Cellular response to insulin stimulusIEAbiological_process
GO:0035338Long-chain fatty-acyl-CoA biosynthetic processTASbiological_process
GO:0042803Protein homodimerization activityIDA IEAmolecular_function
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0048545Response to steroid hormoneIEAbiological_process
GO:0048666Neuron developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.53342789790.96538812740.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1745739786
GSE13712_SHEARDown-0.0316638396
GSE13712_STATICUp0.0028704503
GSE19018Up0.0812498242
GSE19899_A1Up0.0546596821
GSE19899_A2Up0.0269985776
PubMed_21979375_A1Up0.3217579641
PubMed_21979375_A2Up0.0901327605
GSE35957Up0.0755435115
GSE36640Down-0.0086038842
GSE54402Up0.0619916162
GSE9593Up0.1007479734
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.0171909629
GSE28863_A2Up0.0460561224
GSE28863_A3Up0.1598565787
GSE28863_A4Up0.0499559343
GSE48662Down-0.0073813435

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-34a-5pMIMAT0000255MIRT025504ProteomicsFunctional MTI (Weak)21566225
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.