HCSGD entry for ARHGAP26

1. General information

Official gene symbolARHGAP26
Entrez ID23092
Gene full nameRho GTPase activating protein 26
Other gene symbolsGRAF GRAF1 OPHN1L OPHN1L1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005100Rho GTPase activator activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005543Phospholipid bindingIDAmolecular_function
GO:0005575Cellular_componentNDcellular_component
GO:0005622IntracellularIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005925Focal adhesionIEAcellular_component
GO:0007165Signal transductionIEAbiological_process
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0007399Nervous system developmentNASbiological_process
GO:0008093Cytoskeletal adaptor activityIEAmolecular_function
GO:0017124SH3 domain bindingIEAmolecular_function
GO:0030036Actin cytoskeleton organizationNASbiological_process
GO:0032320Positive regulation of Ras GTPase activityNASbiological_process
GO:0032321Positive regulation of Rho GTPase activityNASbiological_process
GO:0043085Positive regulation of catalytic activityNASbiological_process
GO:0043547Positive regulation of GTPase activityNASbiological_process
GO:0046847Filopodium assemblyIEAbiological_process
GO:0050790Regulation of catalytic activityNASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00066149460.99834458040.07406329111.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1429138022
GSE13712_SHEARUp1.0799850009
GSE13712_STATICUp0.9708159975
GSE19018Up0.2186506605
GSE19899_A1Up0.4355214805
GSE19899_A2Up1.0449535022
PubMed_21979375_A1Up1.3794117205
PubMed_21979375_A2Up1.6366784699
GSE35957Down-0.0575574999
GSE36640Up0.5240240230
GSE54402Up0.2713354374
GSE9593Up0.5530110706
GSE43922Up1.3646428771
GSE24585Up0.2153852612
GSE37065Down-0.0227792193
GSE28863_A1Up0.4426734232
GSE28863_A2Up0.5402836279
GSE28863_A3Up0.3297398834
GSE28863_A4Up0.0860714914
GSE48662Up0.3326547374

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-324-3pMIMAT0000762MIRT042845CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044784CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052044CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.