HCSGD entry for F8
1. General information
| Official gene symbol | F8 |
|---|---|
| Entrez ID | 2157 |
| Gene full name | coagulation factor VIII, procoagulant component |
| Other gene symbols | AHF DXS1253E F8B F8C FVIII HEMA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002576 | Platelet degranulation | TAS | biological_process |
| GO:0004252 | Serine-type endopeptidase activity | IEA | molecular_function |
| GO:0005507 | Copper ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | NAS TAS | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006953 | Acute-phase response | IEA | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0007597 | Blood coagulation, intrinsic pathway | TAS | biological_process |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0030168 | Platelet activation | TAS | biological_process |
| GO:0031093 | Platelet alpha granule lumen | TAS | cellular_component |
Entries Per Page
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1138025607 | 0.5831327001 | 0.6939145008 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0634489872 |
| GSE13712_SHEAR | Up | 0.2815226123 |
| GSE13712_STATIC | Up | 0.6247193899 |
| GSE19018 | Down | -0.0327870515 |
| GSE19899_A1 | Up | 0.1244461831 |
| GSE19899_A2 | Down | -0.1927139284 |
| PubMed_21979375_A1 | Down | -0.1865017837 |
| PubMed_21979375_A2 | Up | 0.3238882156 |
| GSE35957 | Up | 0.0983501408 |
| GSE36640 | Up | 0.0000256219 |
| GSE54402 | Down | -0.3052476023 |
| GSE9593 | Up | 0.5892737179 |
| GSE43922 | Up | 0.0244253065 |
| GSE24585 | Up | 0.6232566867 |
| GSE37065 | Up | 0.1199564793 |
| GSE28863_A1 | Down | -0.2847937431 |
| GSE28863_A2 | Up | 0.0075018719 |
| GSE28863_A3 | Down | -0.0966020273 |
| GSE28863_A4 | Up | 0.0002519806 |
| GSE48662 | Up | 0.2757931484 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Coagulation Factor IX (Recombinant) | DB00100 | BTD00038 | BIOD00038 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
