HCSGD entry for AGXT

1. General information

Official gene symbolAGXT
Entrez ID189
Gene full namealanine-glyoxylate aminotransferase
Other gene symbolsAGT AGT1 AGXT1 PH1 SPAT SPT TLH6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004760Serine-pyruvate transaminase activityIEAmolecular_function
GO:0005102Receptor bindingIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005759Mitochondrial matrixIEAcellular_component
GO:0005777PeroxisomeIDAcellular_component
GO:0005782Peroxisomal matrixIDA TAScellular_component
GO:0006625Protein targeting to peroxisomeIMPbiological_process
GO:0008453Alanine-glyoxylate transaminase activityIDA TASmolecular_function
GO:0008483Transaminase activityIDAmolecular_function
GO:0009436Glyoxylate catabolic processIDAbiological_process
GO:0016597Amino acid bindingIDAmolecular_function
GO:0019265Glycine biosynthetic process, by transamination of glyoxylateIDAbiological_process
GO:0019448L-cysteine catabolic processIDAbiological_process
GO:0030170Pyridoxal phosphate bindingIDA IMPmolecular_function
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0042853L-alanine catabolic processIDAbiological_process
GO:0042866Pyruvate biosynthetic processIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046487Glyoxylate metabolic processIMP TASbiological_process
GO:0046724Oxalic acid secretionIEAbiological_process
GO:0051384Response to glucocorticoidIEAbiological_process
GO:0051591Response to cAMPIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.85078204100.69779949470.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0371520342
GSE13712_SHEARDown-0.0880004318
GSE13712_STATICUp0.0273790827
GSE19018Up0.0339338229
GSE19899_A1Down-0.0305424339
GSE19899_A2Down-0.0132255990
PubMed_21979375_A1Down-0.0009183236
PubMed_21979375_A2Down-0.0903302467
GSE35957Up0.0402289941
GSE36640Down-0.0579551562
GSE54402Down-0.0760248922
GSE9593Down-0.0487193357
GSE43922Down-0.0364813414
GSE24585Up0.0464356585
GSE37065Down-0.0392852986
GSE28863_A1Down-0.2167677994
GSE28863_A2Up0.0511832443
GSE28863_A3Up0.3852466413
GSE28863_A4Up0.2175636710
GSE48662Down-0.0147111755

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

GlycineDB00145 NUTR00028
L-AlanineDB00160 NUTR00013
Aminooxyacetic acidDB02079 EXPT00528
N'-Pyridoxyl-Lysine-5'-MonophosphateDB04083 EXPT02040
4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACIDDB08060 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.