HCSGD entry for DNM2

1. General information

Official gene symbolDNM2
Entrez ID1785
Gene full namedynamin 2
Other gene symbolsCMT2M CMTDI1 CMTDIB DI-CMTB DYN2 DYNII
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleNASbiological_process
GO:0000139Golgi membraneTAScellular_component
GO:0003924GTPase activityIEA NAS TASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005525GTP bindingIEA NASmolecular_function
GO:0005829CytosolTAScellular_component
GO:0005874MicrotubuleIDA IEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006184GTP catabolic processNAS TASbiological_process
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0006892Post-Golgi vesicle-mediated transportTASbiological_process
GO:0006897EndocytosisIEA NASbiological_process
GO:0007165Signal transductionNASbiological_process
GO:0008017Microtubule bindingNASmolecular_function
GO:0014069Postsynaptic densityIEAcellular_component
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0019899Enzyme bindingNASmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0030496MidbodyIEAcellular_component
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0031623Receptor internalizationIMPbiological_process
GO:0033572Transferrin transportIMPbiological_process
GO:0043065Positive regulation of apoptotic processNASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045211Postsynaptic membraneIDAcellular_component
GO:0045893Positive regulation of transcription, DNA-templatedNASbiological_process
GO:0046209Nitric oxide metabolic processTASbiological_process
GO:0048489Synaptic vesicle transportNASbiological_process
GO:0050999Regulation of nitric-oxide synthase activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.24460831660.84480623080.93273324641.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0282557239
GSE13712_SHEARDown-0.1149667634
GSE13712_STATICDown-0.0787221897
GSE19018Down-0.0962904715
GSE19899_A1Down-0.1001893540
GSE19899_A2Up0.2659859845
PubMed_21979375_A1Up0.8879573530
PubMed_21979375_A2Up0.8529567136
GSE35957Up0.0074364966
GSE36640Up0.0481514892
GSE54402Up0.1565345671
GSE9593Down-0.0232812241
GSE43922Down-0.0655833157
GSE24585Up0.0122092523
GSE37065Down-0.1065336263
GSE28863_A1Up0.2940017398
GSE28863_A2Up0.2150078280
GSE28863_A3Down-0.0791715323
GSE28863_A4Up0.0487527657
GSE48662Up0.4278621863

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT002670MicroarrayFunctional MTI (Weak)15685193
hsa-miR-124-3pMIMAT0000422MIRT002670Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-130a-3pMIMAT0000425MIRT007139qRT-PCRFunctional MTI (Weak)23418453
hsa-miR-615-3pMIMAT0003283MIRT040188CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049062CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.