HCSGD entry for DDX1

1. General information

Official gene symbolDDX1
Entrez ID1653
Gene full nameDEAD (Asp-Glu-Ala-Asp) box helicase 1
Other gene symbolsDBP-RB UKVH5d
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000245Spliceosomal complex assemblyNASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003682Chromatin bindingIDAmolecular_function
GO:0003712Transcription cofactor activityIDAmolecular_function
GO:0003724RNA helicase activityTASmolecular_function
GO:0003725Double-stranded RNA bindingIEAmolecular_function
GO:0004518Nuclease activityIDAmolecular_function
GO:0004527Exonuclease activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006200ATP catabolic processIDAbiological_process
GO:0006302Double-strand break repairIDAbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006446Regulation of translational initiationNASbiological_process
GO:0007275Multicellular organismal developmentIEPbiological_process
GO:0008026ATP-dependent helicase activityIDAmolecular_function
GO:0008143Poly(A) bindingIDAmolecular_function
GO:0009615Response to virusIEAbiological_process
GO:0010494Cytoplasmic stress granuleIDAcellular_component
GO:0030529Ribonucleoprotein complexIDAcellular_component
GO:0032508DNA duplex unwindingIDAbiological_process
GO:0033677DNA/RNA helicase activityIDAmolecular_function
GO:0043330Response to exogenous dsRNAIEAbiological_process
GO:0071920Cleavage bodyIDAcellular_component
GO:0072669TRNA-splicing ligase complexIDAcellular_component
GO:0090305Nucleic acid phosphodiester bond hydrolysisIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94205005130.05848244750.99999024730.4548807624

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2943267931
GSE13712_SHEARDown-0.1772657049
GSE13712_STATICDown-0.0196818663
GSE19018Down-0.2706249571
GSE19899_A1Down-0.2446119070
GSE19899_A2Down-0.3220485121
PubMed_21979375_A1Down-0.0768512001
PubMed_21979375_A2Up0.1306754098
GSE35957Down-0.2639736917
GSE36640Down-0.1852278370
GSE54402Up0.0837044597
GSE9593Down-0.3322332451
GSE43922Down-0.2001972730
GSE24585Down-0.3654364006
GSE37065Down-0.1648160667
GSE28863_A1Up0.0342584052
GSE28863_A2Up0.4392184800
GSE28863_A3Down-0.6220678829
GSE28863_A4Down-0.1762317640
GSE48662Down-0.5074512232

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1260aMIMAT0005911MIRT035849CLASHFunctional MTI (Weak)23622248
hsa-miR-342-5pMIMAT0004694MIRT038224CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.