HCSGD entry for DCK


1. General information

Official gene symbolDCK
Entrez ID1633
Gene full namedeoxycytidine kinase
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004137Deoxycytidine kinase activityIDAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006139Nucleobase-containing compound metabolic processIEAbiological_process
GO:0006144Purine nucleobase metabolic processTASbiological_process
GO:0006206Pyrimidine nucleobase metabolic processTASbiological_process
GO:0006220Pyrimidine nucleotide metabolic processIDAbiological_process
GO:0008144Drug bindingIDAmolecular_function
GO:0009157Deoxyribonucleoside monophosphate biosynthetic processIDA TASbiological_process
GO:0009165Nucleotide biosynthetic processEXP IDA TASbiological_process
GO:0016773Phosphotransferase activity, alcohol group as acceptorIEAmolecular_function
GO:0019206Nucleoside kinase activityEXPmolecular_function
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0043097Pyrimidine nucleoside salvageTASbiological_process
GO:0043101Purine-containing compound salvageTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0055086Nucleobase-containing small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91220800120.00060935370.99999024730.0463549133

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.4533964074
GSE13712_SHEARDown-0.0000495453
GSE13712_STATICDown-0.0556398052
GSE19018Up0.1448198386
GSE19899_A1Down-1.0742914091
GSE19899_A2Down-1.6790191242
PubMed_21979375_A1Down-0.4285932195
PubMed_21979375_A2Down-1.9921035195
GSE35957Down-0.5637826370
GSE36640Down-1.9765802021
GSE54402Down-0.3748730571
GSE9593Down-0.3624781574
GSE43922Down-0.7042906845
GSE24585Up0.1173198683
GSE37065Down-0.3015187101
GSE28863_A1Up1.0856154969
GSE28863_A2Down-0.7559631889
GSE28863_A3Down-0.1322006270
GSE28863_A4Down-0.5639601388
GSE48662Down-0.9722633022

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

FludarabineDB01073 APRD00594
2'-DeoxycytidineDB02594 EXPT01140
CP-4055DB05494 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019296MicroarrayFunctional MTI (Weak)17612493
hsa-miR-128-3pMIMAT0000424MIRT021886MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.