HCSGD entry for TTC8

1. General information

Official gene symbolTTC8
Entrez ID123016
Gene full nametetratricopeptide repeat domain 8
Other gene symbolsBBS8 RP51
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001103RNA polymerase II repressing transcription factor bindingIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0005929CiliumIDAcellular_component
GO:0007411Axon guidanceIEAbiological_process
GO:0007608Sensory perception of smellIEAbiological_process
GO:0015031Protein transportIEAbiological_process
GO:0021772Olfactory bulb developmentIEAbiological_process
GO:0032391Photoreceptor connecting ciliumIEAcellular_component
GO:0032880Regulation of protein localizationIEAbiological_process
GO:0034464BBSomeIDA IEAcellular_component
GO:0035264Multicellular organism growthIEAbiological_process
GO:0036064Ciliary basal bodyIDAcellular_component
GO:0042384Cilium assemblyIEA TASbiological_process
GO:0045444Fat cell differentiationIEAbiological_process
GO:0048560Establishment of anatomical structure orientationIMPbiological_process
GO:0050893Sensory processingTASbiological_process
GO:0060170Ciliary membraneIEAcellular_component
GO:0060219Camera-type eye photoreceptor cell differentiationIEAbiological_process
GO:0061326Renal tubule developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62463645000.19827802140.99999024730.8610585382

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0943550551
GSE13712_SHEARDown-0.1213683330
GSE13712_STATICDown-0.1127574038
GSE19018Up0.3782656572
GSE19899_A1Down-0.3334117171
GSE19899_A2Up0.0171970571
PubMed_21979375_A1Down-1.4692641844
PubMed_21979375_A2Down-0.3732453274
GSE35957Up0.2310325918
GSE36640Down-0.1867008504
GSE54402Up0.0447939787
GSE9593Up0.3600444247
GSE43922Down-0.4526646572
GSE24585Up0.1157221435
GSE37065Up0.2084019552
GSE28863_A1Up0.0239634161
GSE28863_A2Down-0.0320739056
GSE28863_A3Down-0.0891333306
GSE28863_A4Up0.0594609013
GSE48662Down-0.3115037317

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-373-3pMIMAT0000726MIRT002556Microarray//Microarray;OtherFunctional MTI (Weak)15685193
hsa-miR-124-3pMIMAT0000422MIRT022749MicroarrayFunctional MTI (Weak)18668037
hsa-miR-125a-3pMIMAT0004602MIRT038637CLASHFunctional MTI (Weak)23622248
hsa-miR-197-3pMIMAT0000227MIRT048124CLASHFunctional MTI (Weak)23622248
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-373-3pMIMAT0000726NAhsa-miR-37315685193
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.