HCSGD entry for CREB3

1. General information

Official gene symbolCREB3
Entrez ID10488
Gene full namecAMP responsive element binding protein 3
Other gene symbolsLUMAN LZIP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIDAcellular_component
GO:0000977RNA polymerase II regulatory region sequence-specific DNA bindingIDAmolecular_function
GO:0001558Regulation of cell growthIDAbiological_process
GO:0002230Positive regulation of defense response to virus by hostIDAbiological_process
GO:0003677DNA bindingIDAmolecular_function
GO:0003682Chromatin bindingIDAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDA IMPcellular_component
GO:0005783Endoplasmic reticulumIMPcellular_component
GO:0005789Endoplasmic reticulum membraneIDA IEAcellular_component
GO:0005794Golgi apparatusIMPcellular_component
GO:0005829CytosolIMPcellular_component
GO:0006351Transcription, DNA-templatedIDA IEAbiological_process
GO:0006935ChemotaxisIEAbiological_process
GO:0006986Response to unfolded proteinIEAbiological_process
GO:0006990Positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein responseIDAbiological_process
GO:0008140CAMP response element binding protein bindingIDAmolecular_function
GO:0016020MembraneIDAcellular_component
GO:0016021Integral component of membraneIDA IEAcellular_component
GO:0016032Viral processIEAbiological_process
GO:0016604Nuclear bodyIDAcellular_component
GO:0019043Establishment of viral latencyIDAbiological_process
GO:0019046Release from viral latencyIDA TASbiological_process
GO:0030176Integral component of endoplasmic reticulum membraneIDAcellular_component
GO:0030335Positive regulation of cell migrationIMPbiological_process
GO:0031726CCR1 chemokine receptor bindingIDAmolecular_function
GO:0034976Response to endoplasmic reticulum stressIDAbiological_process
GO:0042127Regulation of cell proliferationIMPbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0042994Cytoplasmic sequestering of transcription factorIDAbiological_process
GO:0043025Neuronal cell bodyIDAcellular_component
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045786Negative regulation of cell cycleNASbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046983Protein dimerization activityTASmolecular_function
GO:0050930Induction of positive chemotaxisIDA IMPbiological_process
GO:0051928Positive regulation of calcium ion transportIMPbiological_process
GO:0090026Positive regulation of monocyte chemotaxisIDAbiological_process
GO:0090045Positive regulation of deacetylase activityIDAbiological_process
GO:2000326Negative regulation of ligand-dependent nuclear receptor transcription coactivator activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09193344100.20919243950.63769283270.8845227631

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.3444702640
GSE13712_SHEARUp0.2228506726
GSE13712_STATICUp0.1097195295
GSE19018Down-0.3657049733
GSE19899_A1Down-0.7432130657
GSE19899_A2Down-0.2819732098
PubMed_21979375_A1Up0.2085703009
PubMed_21979375_A2Down-0.7910983789
GSE35957Up0.1219950083
GSE36640Up0.6114393257
GSE54402Up0.2588145740
GSE9593Up0.8239682937
GSE43922Down-0.0450658160
GSE24585Up0.4825464384
GSE37065Up0.1173357811
GSE28863_A1Down-0.0951056637
GSE28863_A2Down-0.3359804880
GSE28863_A3Down-0.4773610954
GSE28863_A4Up0.0143265193
GSE48662Up0.0388720730

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT019911MicroarrayFunctional MTI (Weak)20215506
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.