HCSGD entry for SCO2

1. General information

Official gene symbolSCO2
Entrez ID9997
Gene full nameSCO2 cytochrome c oxidase assembly protein
Other gene symbolsCEMCOX1 SCO1L
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001654Eye developmentIMPbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0003012Muscle system processIEAbiological_process
GO:0005507Copper ion bindingNASmolecular_function
GO:0005739MitochondrionIEA TAScellular_component
GO:0005743Mitochondrial inner membraneIEAcellular_component
GO:0006825Copper ion transportIEAbiological_process
GO:0006878Cellular copper ion homeostasisIEAbiological_process
GO:0008535Respiratory chain complex IV assemblyIEAbiological_process
GO:0014823Response to activityIEAbiological_process
GO:0022904Respiratory electron transport chainIEAbiological_process
GO:0030016MyofibrilIDAcellular_component
GO:0055070Copper ion homeostasisIEAbiological_process
GO:0055114Oxidation-reduction processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00094311010.93375324270.08363602691.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.7529397779
GSE13712_SHEARUp0.7083870994
GSE13712_STATICUp0.7312308216
GSE19018Down-0.1491790337
GSE19899_A1Up1.6780494352
GSE19899_A2Up1.7260678098
PubMed_21979375_A1Up4.3764105205
PubMed_21979375_A2Up2.3539032807
GSE35957Down-0.6170820196
GSE36640Up1.1414398449
GSE54402Up0.8120676429
GSE9593Up0.0901862525
GSE43922Up0.5222788681
GSE24585Down-0.0563118528
GSE37065Up0.3055848643
GSE28863_A1Down-0.3927446570
GSE28863_A2Down-0.2394331994
GSE28863_A3Down-0.1397558849
GSE28863_A4Down-0.0350119427
GSE48662Up0.0885658742

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029944MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.