HCSGD entry for WDR1
1. General information
| Official gene symbol | WDR1 |
|---|---|
| Entrez ID | 9948 |
| Gene full name | WD repeat domain 1 |
| Other gene symbols | AIP1 NORI-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002102 | Podosome | IEA | cellular_component |
| GO:0002576 | Platelet degranulation | TAS | biological_process |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0007605 | Sensory perception of sound | TAS | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030168 | Platelet activation | TAS | biological_process |
| GO:0042995 | Cell projection | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9833995365 | 0.0338291402 | 0.9999902473 | 0.3473277929 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7538138666 |
| GSE13712_SHEAR | Up | 0.1374595053 |
| GSE13712_STATIC | Down | -0.1003664970 |
| GSE19018 | Down | -0.2244079918 |
| GSE19899_A1 | Down | -0.3385263450 |
| GSE19899_A2 | Down | -0.0406406501 |
| PubMed_21979375_A1 | Down | -0.2074902072 |
| PubMed_21979375_A2 | Down | -0.7467032031 |
| GSE35957 | Up | 0.3397258983 |
| GSE36640 | Down | -0.2413608370 |
| GSE54402 | Up | 0.0182369092 |
| GSE9593 | Up | 0.0428564359 |
| GSE43922 | Up | 0.0069720393 |
| GSE24585 | Down | -0.3828859317 |
| GSE37065 | Down | -0.2557811897 |
| GSE28863_A1 | Down | -0.1137683113 |
| GSE28863_A2 | Down | -0.2525631576 |
| GSE28863_A3 | Down | -0.1190120934 |
| GSE28863_A4 | Down | -0.0401916221 |
| GSE48662 | Down | -0.2502685076 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019985 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028095 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036411 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036948 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039865 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049572 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23466301 | These genes, PDIA3, WDR1, FSTL1, COPG1, LMAN1, and PDIA6, significantly downregulated |
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