HCSGD entry for OXSR1
1. General information
| Official gene symbol | OXSR1 |
|---|---|
| Entrez ID | 9943 |
| Gene full name | oxidative stress responsive 1 |
| Other gene symbols | OSR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IDA | molecular_function |
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IDA | molecular_function |
| GO:0004702 | Receptor signaling protein serine/threonine kinase activity | IBA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IDA IEA | molecular_function |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0006979 | Response to oxidative stress | IEA | biological_process |
| GO:0023014 | Signal transduction by phosphorylation | IBA | biological_process |
| GO:0035556 | Intracellular signal transduction | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4834138863 | 0.1877766574 | 0.9999902473 | 0.8399991672 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0740043552 |
| GSE13712_SHEAR | Down | -0.0307884262 |
| GSE13712_STATIC | Up | 0.0423082049 |
| GSE19018 | Up | 0.3982618342 |
| GSE19899_A1 | Down | -0.1232710682 |
| GSE19899_A2 | Up | 0.4447667740 |
| PubMed_21979375_A1 | Up | 0.1690555798 |
| PubMed_21979375_A2 | Up | 0.2781389490 |
| GSE35957 | Down | -0.1277708885 |
| GSE36640 | Down | -0.4688628310 |
| GSE54402 | Up | 0.2172794591 |
| GSE9593 | Up | 0.1330455704 |
| GSE43922 | Down | -0.1048208825 |
| GSE24585 | Down | -0.2437738866 |
| GSE37065 | Up | 0.3032409618 |
| GSE28863_A1 | Down | -0.0149004794 |
| GSE28863_A2 | Up | 0.5901071920 |
| GSE28863_A3 | Down | -0.5838149775 |
| GSE28863_A4 | Down | -0.2736476520 |
| GSE48662 | Down | -0.6901784405 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029769 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030472 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043941 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
